The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his ...
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources ...
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over ...
The mission of the Industrial Partnership team is to detect, promote, assist and protect the inventive activities from research (inventions, know-how and biological materials) conducted at the Institut Pasteur (and in some Institutes of its international network), and transfer there to industrial ...
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study ...
Pasteur course: Human population genomics and genetic epidemiology
This two-week course presents theoretical lectures, research examples and hands-on computer training on concepts and tools used in the study of human population genomics and genetic epidemiology.
The first week consists in three days of both theoretical lectures and research examples, and two days of hands-on-computer training and discussions presenting the concepts and the technical tools used in both human population genomics and genetic epidemiology.
Introductory concepts in human genomics and populations genetics.
Basic concepts in statistical genetics and genomics.
Introduction to genetic epidemiology.
Population genetics: mutation, recombination and linkage disequilibrium.
Public databases in human genomics (HapMap, 1,000 Genomes).
Genetic epidemiology (linkage analyses and association studies).
Methods to detect natural selection in the human genome.
Lectures from keynote speakers in genetic epidemiology and population genetics.
The second week consists in two days of detailed theoretical bases in population genomics and genetic epidemiology analyses and three days of practical computer-based training in the most recent concepts and analyses used in both disciplines. The practical training (computer laboratory work and discussion of the results) is based on real-data examples, using infectious diseases as a paradigm.
Topics include :
Quantitative genetics and expression quantitative trait loci (eQTL) analysis.
Analysis of rare variants and population structure.