Current call

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The 2014-2015 call for enrollment of students in October 2015 is open.

 

Candidates are advised to read carefully the Application information section for details on the application procedures.

 

The titles of PhD projects and the names of the laboratory heads and thesis directors are listed below. For each project, there is a direct link to a description of the project proposal with contact information. The first step is to apply to the thesis director of the project(s) of interest by sending a CV and a letter of motivation. You may apply to more than one since each thesis director must choose just one candidate to present to the Admissions committee.  

 

Laboratories may be contacted from now until November 7th, the sooner the better. The full applications, prepared jointly by the candidate and the laboratory, are due November 21.  Interviews of selected candidates will take place February 10-13, 2015. Start of the Ph.D.: October 1st, 2015.

 

More information about the scientific interests of the Departments and Laboratories is available at www.pasteur.fr/en/research.

 

The list below may be updated regularly, with the most recent proposals appearing at the end.

 

 

Project number

Title of the PhD project

Lab name / Department

Head of the laboratory

Thesis director

PPU2015-1

Functional contribution of novel molecular effectors on cell  infection by the bacterial pathogen Listeria

Bacteria-Cell Interactions

 

Cell Biology and Infection

Pascale Cossart

Javier Pizarro-Cerda

PPU2015-2

From rod to spiral shape: role of endopeptidases in cell shape determination of Helicobacter pylori

Biology and Genetics of the Bacterial Cell Wall

 

Microbiology

Ivo Gomperts Boneca

Nienke Buddelmeijer

PPU2015-3

Optical dissection of cerebellar sensory processing in mouse models of Autism

Dynamic Neuronal Imaging

 

Neuroscience

David DiGregorio

David DiGregorio

PPU2015-4

Molecular bases of the invasion of the central nervous system by Listeria monocytogenes

Biology of Infection

 

Infection and Epidemiology

Marc Lecuit

Marc Lecuit

PPU2015-5

Super-resolution imaging of chromosomes or HIV

Imaging and Modeling

 

Cell Biology and Infection

Christophe Zimmer

Christophe Zimmer

PPU2015-6

Flagellum sensing during the early steps of mammalian host infection by African trypanosomes

Trypanosome cell biology

 

Parasitology and Mycology

Philippe Bastin

Brice Rotureau

PPU2015-7

Study of escape of immune responses by Leptospira interrrogans and consequences of chronic renal colonization in mice

Biology and Genetic of Bacterial Cell Wall

 

Microbiology

Ivo Gomperts Boneca

Catherine Werts

PPU2015-8

Molecular mechanism of induction and characterization of IL-10-producing CD4 T cells promoted by type I interferon - Relevance in multiple sclerosis

Cytokine Signaling

 

Immunology

Sandra Pellegrini

Frédérique Michel

PPU2015-9

Role of transcription factor NF-YA in cell fate decisions

Nuclear Organisation and Oncogenesis

 

Cell Biology and Infection

Anne Dejean

Oliver Bischof

PPU2015-10

Cervical cancer and the APOBEC3B mutator gene polymorphism

Molecular Retrovirology

 

Virology

Simon Wain-Hobson

Jean-Pierre Vartanian

PPU2015-11

Study of alternative polyadenylation regulation in the pathogenic yeast Cryptococcus neoformans

Fungal Biology and Pathogenicity

 

Genomes & Genetics

Christophe d’Enfert

Guilhem Janbon

PPU2015-12

PTEN function in directed migration

Cell Polarity, Migration and Cancer

 

Cell Biology and Infection

Sandrine Etienne-Manneville

Sandrine Etienne-Manneville

PPU2015-13

Induction of trinucleotide repeat contractions by TALEN and CRIPSR-Cas nucleases

Yeast Molecular Genetics

 

Genomes & Genetics

Bernard Dujon

Guy-Franck Richard

PPU2015-14

Disease mechanisms and therapy of the hearing deficit in the USH syndrome type III (deaf-blindness in humans): insights from animal models

Genetic and Physiology of Audition

 

Neuroscience

Christine Petit

Aziz El Amraoui

PPU2015-15

Hierarchy of the DNA repair pathways during quiescence

Dynamics of the genomes

 

Genomes & Genetics

Benoît Arcangioli

Benoît Arcangioli

PPU2015-16

Non coding RNAs and epigenetic in the regulation of the alternative splicing

Epigenetic Regulation

 

Developmental and Stem Cell Biology

Christian Muchardt

Eric Batsché

PPU2015-17

Establishment of the T cell compartment: two waves of thymic settling progenitors.

Lymphopoiesis

 

Immunology

Ana Cumano

Ana Cumano

PPU2015-18

Targeting Extended-Synaptotagmin 2 in ABC-Diffuse large B-cell lymphoma

Signaling and Pathogenesis

 

Cell Biology and infection

Robert Weil

Robert Weil

PPU2015-19

Mechanism of regulation of IMPDH, a key enzyme of the guanine nucleotides metabolism

Chemistry and Biocatalysis

 

Structural Biology and Chemistry

Sylvie Pochet

Hélène Munier-Lehmann

PPU2015-20

Cellular components specifically targeted by Yersinia pestis

Yersinia Research

 

Microbiology

Elisabeth Carniel

Elisabeth Carniel

PPU2015-21

Modeling Translocation-induced lymphoid cancers using genome editing technology

Lymphocyte Development & Oncogenesis

 

Immunology

Ludovic Deriano

Ludovic Deriano

PPU2015-22

Stress response and virulence in the pathogen Leptospira interrogans.

Biology of spirochetes

 

Microbiology

Mathieu Picardeau

Mathieu Picardeau/Nadia Benaroudj

PPU2015-23

Deciphering bacterial virulence pathways with the help of CRISPR

Synthetic Biology

 

Microbiology

David Bikard

David Bikard

PPU2015-24

Control of bacterial cell shape

Bacterial Morphogenesis and Growth

 

Microbiology

Sven van Teeffelen

Sven van Teeffelen

PPU2015-25

Membrane Traffic and Cell Division in normal and pathological situations.

Membrane Traffic and Cell Division

 

Cell Biology and Infection

Arnaud Echard

Arnaud Echard

PPU2015-26

Mechanisms of food allergy and oral immunotherapy

Antibodies in Therapy and Pathology

 

Immunology

Pierre Bruhns

Pierres Bruhns/Laurent Reber

PPU2015-27

Epigenetic regulation of gene expression associated with protection during non-progressive HIV/SIV infection

HIV, inflammation and persistence

 

Virology

Michaela Müller-Trutwin

Michaela Müller-Trutwin

PPU2015-28

Blocking the Homing of Malaria Sporozoites to the Liver

Malaria Biology and Genetics

 

Parasitology and Mycology

Robert Ménard

Robert Ménard

PPU2015-29

Meta-analysis of infection

Spatial Regulation of Genomes

 

Genomes & Genetics

Romain Koszul

Romain Koszul

PPU2015-30

Novel Proteomics Approaches for the Identification of Bacterial Pathogens

Structural Mass Spectrometry and Proteomics

 

Structural Biology and Chemistry

Julia Chamot-Rooke

Julia Chamot-Rooke

PPU2015-31

Maternal effects and Plasmodium receptivity in Anopheles mosquitoes

Functional Genetics of Infectious Diseases

 

Genomes & Genetics

Anavaj Sakuntabhai

Catherine Bourgouin

PPU2015-32

Interactions between nuclear pore complex and chromatin required for HIV-1 replication.

Molecular Virology and Vaccinology

 

Virology

Pierre Charneau

Francesca Di Nunzio/Marc Lavigne

PPU2015-33

The role of nicotinic receptors in Alzheimer’s Disease pathology and treatment

Integrative Neurobiology of Cholinergic Systems

 

Neuroscience

Uwe Maskos

Uwe Maskos

PPU2015-34

Structural characterisation of Type VII secretion systems involved in mycobacterial invasion

Structural Biology of Bacterial Secretion Systems

 

Structural Biology and Chemistry

Rémi Fronzes

Francesca Gubellini

PPU2015-35

Molecular mechanisms of human antigen CD20

Molecular Mechanisms of Membrane Transport

 

Structural Biology and Chemistry

Nicolas Reyes

Nicolas Reyes

PPU2015-36

Role of virulent bacteriophages on gut bacterial populations

Molecular Biology of the Gene in Extremophiles

 

Microbiology

Patrick Forterre

Laurent Debarbieux

PPU2015-38

Hyperthermophilic archaeal viruses as scaffolds for bionanomaterial development

Molecular Biology of the Gene in Extremophiles

 

Microbiology

Patrick Forterre

Mart Krupovic/David Prangishvili

PPU2015-39

Mechanism of action of TSLP

Lymphopoiesis

 

Immunology

Ana Cumano

Paulo Vieira

PPU2015-40

Optimization of therapeutic vaccination against cancer

Immune regulation and Vaccinology

 

Immunology

Claude Leclerc

Gilles Dadaglio

PPU2015-41

Dissecting the interface between influenza virus and the cellular splicing machinery

Molecular Genetics of RNA Viruses

 

Virology

Sylvie van der Werf

Nadia Naffakh

PPU2015-42

Mechanism of cell division orientation underlying cardiac chamber expansion

Heart Morphogenesis

 

Developmental and Stem Cell Biology

Sigolène Meilhac

Sigolène Meilhac

PPU2015-43

Structure and function of a metabolic multi-protein ‘supercomplex’ in Actinobacteria

Structural Microbiology

 

Structural Biology and Chemistry

Pedro Alzari

Pedro Alzari / Marco Bellinzoni

PPU2015-44

ExoY, a nucleotidyl cyclase toxin from Pseudomonas aeruginosa

Biochemistry of Macromolecular Interactions

 

Structural Biology and Chemistry

Daniel Ladant

Undine Mechold

PPU2015-45

Contactins and neural disease: ligand/receptor and signaling interactions at the synapse with protein tyrosine phosphatases

Integrative Neurobiology of Cholinergic Systems

 

Neuroscience

Uwe Maskos

Sheila Harroch

PPU2015-46

Exploring immunological mechanisms of graft-versus-host disease and of functional immune tolerance in patients after allogeneic hematopoietic stem cell transplantation

Immunoregulation

 

Immunology

Lars Rogge

Lars Rogge

PPU2015-47

Transport of nickel, a virulence determinant of the gastric pathogen Helicobacter pylori

Helicobacter pathogenesis

 

Microbiology

Hilde de Reuse

Daniel Vinella

PPU2015-48

Study of signaling pathways involved in the control of HIV replication by NK cells

Regulation of Retroviral Infections

 

Virology

Françoise Barré-Sinoussi

Daniel Scott-Algara

PPU2015-49

Design of synthetic carbohydrate-based conjugates toward a broad coverage Shigella vaccine

Chemistry of Biomolecules

 

Structural Biology and Chemistry

Laurence Mulard

Laurence Mulard

PPU2015-50

Allosteric transitions of nicotinic acetylcholine receptors explored by combined biophysical approaches

Channel-Receptors

 

Neuroscience

Pierre-Jean Corringer

Pierre-Jean Corringer

Updated on 19/09/2014