Publications 2001-2014



Malbec M, Mouquet H, Schwartz O. 2014 Les anticorps anti-VIH-1 et la transmission virale de cellule à cellule. médecine/ sciences (Paris) 30:508-510. Abstract


Briolat V, Jouneau L, Carvalho R, Palha N, Langevin C, Herbomel P, Schwartz O, Spaink HP, Levraud JP, Boudinot P. 2014. Contrasted Innate Responses to Two Viruses in Zebrafish: Insights into the Ancestral Repertoire of Vertebrate IFN-Stimulated Genes. J Immunol 192:4328-4341. Abstract


Zhang X, Casartelli N, Lemoine S, Mozeleski B, Azria E, Le Ray C, Schwartz O, Launay O, Leclerc C, Lo-Man R. 2014. Plasmacytoid DC engagement by Flu vaccine as a surrogate strategy for driving Th1 responses in human neonatal settings. The Journal of infectious diseases.  10.1093/infdis/jiu103. Abstract


Vabret N, Bailly-Bechet M, Lepelley A, Najburg V, Schwartz O, Verrier B, Tangy F. 2014. Large-scale nucleotide optimization of simian immunodeficiency virus (SIV) reduces its capacity to stimulate type-I IFN in vitro. J Virol. 10.1128/JVI.03223-13. Abstract




Malbec M, Porrot F, Rua R, Horwitz J, Klein F, Halper-Stromberg A, Scheid J, Eden C, Mouquet H, Nussenzweig MC, Schwartz O. 2013. Broadly neutralizing antibodies that inhibit HIV-1 cell-to-cell transmission. J. Exp. Med. Dec 16;210(13):2813-21. Abstract


Rey F, Schwartz O, Wain-Hobson S Gain-of-function research. Unknown risks.  Science 2013 Oct 18;342(6156):311. Abstract

Cruz DJM, Bonotto RM, Gomes R, da Silva CT, Taniguchi JB, Hwan No J, Lombardot B, Schwartz O, Hansen MA, Freitas-Junior LH "Identification of Novel Compounds Inhibiting Chikungunya Virus-induced Cell Death by High Throughput Screening of a Kinase Inhibitor Library" PLoS Negl Trop Dis. 2013 Oct 31;7(10):e2471. Abstract


Horwitz, JA. Halper-Stromberg, A. Mouquet, H. Gitlin, AD. Tretiakova, A. Eisenreich, TR. Malbec, M. Gravemann, S. Billerbeck, E. Dorner, M. Buning, H. Schwartz, O. Knops, E. Kaiser, R. Seaman, MS. Wilson, JM. Rice, CM. Ploss, A. Bjorkman, PJ. Klein, F. Nussenzweig, MC. (2013). HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc Natl Acad. Abstract.

Palha, N. Guivel-Benhassine, F. Briolat, V. Lutfalla, G. Sourisseau, M. Ellet, F. Wang, CH. Lieschke, GJ. Herbomel, P. Schwartz, O.Levraud, JP. (2013). Real-time whole-body visualization of chikungunya virus infection and host interferon response in zebrafish.
Plos Pathogen 9:e1003619. Abstract.

Roesch, F. Schwartz, O. (2013). The SAMHD1 knockout mouse model : in vivo veritas ?.
EMBO journal 32:2427-2429. Abstract.

Malbec, M. Sourisseau, M. Guivel-Benhassine, F. Blanchet, F. Porrot, F. Schwartz O and Casartelli, N. (2013). HIV-1 Nef promotes the localization of Gag at the cell membrane and facilitates viral cell-to-cell transfer. Retrovirology Jul 30;10:80.doi:10.1186/1742-4690-10-80. Abstract.

Castelli, FA. Szely, N. Olivain, A. Casartelli, N. Grygar, C. Schneider, A. Besse, A. Levy, Y. Schwartz, O and Maillère, B. (2013). Hierarchy of CD4 T cell epitopes of the ANRS Lipo5 synthetic vaccine relies on the frequencies of pre-existing peptide-specific T cells in healthy donors.
Journal of Immunology 190(11):5757-63. Abstract.

Zhang, X. Lepelley, A. Azria, E. Lebon, G. Roguet, O. Schwartz, O. Launay, C. Leclerc and Lo-Man R. (2013). Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses. Plos One 8:e52003. Abstract.

El Far, M. Isabelle, C. Chomont, N. Bourbonnière, M. Fonseca, S. Ancuta, P. Peretz, Y. Chouikh, Y. Halwani, R. Schwartz, O. Madrenas, J. Freeman, GJ. Routy, JP. Haddad, EK. Sékaly, RF. (2013). Down-Regulation of CTLA-4 by HIV-1 Nef Protein. Plos One, January, Vol 8, issue 1,e54295. Abstract.

Puigdomenech, I. Casartelli, N. Porrot, F. and Schwartz, O. (2013) SAMHD1 Restricts HIV-1 Cell-to-Cell transmission and limits immune detection in monocyte-derived dendritic cells.
Journal of Virology Mar;87(5):2846-56. Abstract.

Li Wu and Schwartz, O. Editors of a book (springer, Advances in Experimental Medicine and Biology) 2013. HIV interaction with dendritic cells. Infection and Immunity. Abstract.



Puigdomenech, I. Casartelli, N. Porrot, F. Schwartz, O. (2012). SAMHD1 Restricts HIV-1 Cell-to-Cell Transmission and Limits Immune Detection in Monocyte-derived Dendritic Cells. Journal of Virology, 2013,87(5):284656. Epub 2012 Dec 26. Abstract.

Descours, B. Cribier, A. Chable-Bessia, C. Ayinde, D. Rice, G. Crow, Y. Yatim, A. Schwartz, O. Laguette, N. Benkirane, M. (2012). SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4+ T-cells. Retrovirology, Oct 23;9(1):87. Abstract

Meertens, L. Carnec, X. Lecoin, MP. Ramdasi, R. Guivel-Benhassine, F. Lew, E. Lemke, G. Schwartz, O. Amara, A. (2012). The TIM and TAM Families of phosphatidylserine receptors mediate dengue virus entry. Cell Host Microbe, Oct 18;12(4):544-57. Abstract

Garcia, Z. Lemaître, F. van Rooijen, N. Albert, ML. Levy, Y. Schwartz, O. Bousso, P. (2012). Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph borne viral particles. Blood, Oct. 12. Abstract

Ayinde, D. Casartelli, N. Schwartz, O. (2012). Restricting HIV the SAMHD1 way : through nucleotide starvation. Nature Review Microbiology, Oct, 10 (10):675-80 (Epub 2012 Aug 28). Abstract

Joubert, PE. Werneke, S. de la Calle, C. Guivel-Benhassine, F. Giodini, A. Peduto, L. Levine, B. Schwartz, O. Lenschow, D. Albert, ML. (2012). Chikungunya-indiced cell death is limited by ER and oxidative stress-induced autophagy. Autophagy, Aug 1;8(8):1261-3. Abstract

Martin-Latil, S. Gnädig, NF. Mallet, A. Desdouits, M. Guivel-Benhassine, F. Jeannin, P. Prevost, MC. Schwartz, O. Gessain, O. Ozden, S. Ceccaldi, PE. (2012). Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells. Blood, Jul 19;120(3):572-80. Abstract

Roesch, F. Meziane, O. Kula, A. Porrot, F. Anderson, I. Mammano, F. Fassati, A. Marcello, A. Benkirane, M. Schwartz, O. (2012). Hyperthermia stimulates HIV-1 replication. Plos Pathogen, Jul, 8 (7):e1002792 (Epub 2012 Jul 12). Abstract

Joubert, PE. Werneke, SW. de la Calle, C. Guivel-Benhassine, F. Giodini, A. Peduto, L. Levine, B. Schwartz, O. Lenschow, DJ. Albert, ML. (2012). Chikungunya virus-induced autophagy delays caspase-dependent cell death. Journal of Experimental Medicine, May 7;209(5):1029-47. Abstract

Monel, B. Beaumont, E. Vendrame, D. Schwartz, O. Brand, D. Mammano, F. (2012). HIV Cell-toCell Transmission Requires the Production of Infectious Virus Particles and Does Not Proceed through Env-Mediated Fusion Pores. Journal of Virology, April, 86(7):3924-33.
(Epub 2012 Jan 18). Abstract

Schilte, C. Buckwalter MR. Laird, ME. Diamond, MS. Schwartz, O. Albert, ML. (2012). Cutting Edge : Independent Roles for IRF-3 and IRF-7 in Hematopoietic and Nonhematopoietic Cells during Host Response to Chikungunya Infection.
Journal of Immunology, April 1:188(7):2967-71 (Epub 2012 Feb 27). Abstract

Rua, R. Leppeley, A. Gessain, A. and Schwartz O. (2012). Innate sensing of Foamy Viruses by human hematopoietic cells
Journal of Virology,Jan;86(2):909-18 Nov 16 (Epub 2011). Abstract.




Genovesio, A. Kwon, YJ. Windisch, MP. Kim, NY. Choi, SY. Kim, HC. Jung, S. Mammano, F. Perrin, V. Boese, AS. Casartelli, N. Schwartz, O. Nehrbass, U. Emans, N. (2011). Automated genome-wide visual profiling of cellular proteins involved in HIV replication.
Journal of Biomolecular Screening, Oct, 16(9):945-58.  Abstract.

Laguette, N. Sobhian, B. Casartelli, N. Ringeard, M. Chable-Bessia, C. Ségéral, E. Yatim, A. Emiliani, S. Schwartz, O and Benkirane, M. (2011) Samhd1 is a dendritic cell HIV-1 restriction factor counteracted by Vpx. Nature, May, 25Abstract.

Cardinaud, S. Consiglieri, G. Bouziat, R. Urrutia, A. Graff-Dubois, S. Fourati, S. Malet, I. Guergnon, J. Guihot, A. Katlama, C. Autran, B. van Endert, P. Lemonnier, FA. Appay, V. Schwartz, O. Kloetzel, PM and Moris, A. (2011) CTL escape mediated by proteasomal destruction of an HIV cryptic epitope. Plos Pathogens May 7 (5) e 1002049. Abstract.

Malbec, M. Roesch, F and Schwartz, O. (2011) Commentary : A new role for the HTLV-1 p8 Protein : Increasing intercellular Conduits and Viral Cell-to-Cell Transmission. Viruses, March 3. Abstract. 

Lepelley, A. Louis, A. Sourisseau, M. Pothlichet, J. Schilte, C. Chaperot, L. Plumas, J. Randall, RE. Si Tahar, M. Mammano, F. Albert, ML and Schwartz, O. (2011) Innate sensing of HIV-infected cells. Plos Pathogens, Feb 7 (2) e 1001284. Abstract.




Feldmann, J. Schwartz, O. (2010) HIV-1 Virological Synapse : Live Imaging of Transmission.
Viruses, 2, 1666-1680 ; doi:10.3390/v2081666. Abstract.

Schwartz, O. Albert, ML. (2010) Biology and pathogenesis  of Chikungunya virus.
Nature Reviews Microbiology  July, vol 8, 491-500. Abstract.

 Casartelli, N. Sourisseau, M. Feldmann, J. Guivel-Benhassine, F. Mallet, A. Marcelin, AG. Guatelli, J. Schwartz, O. (2010) Tetherin restricts productive HIV-1  cell-to-cell transmission.
Plos Pathogens June, vol 6, Issue 6-e1000955. Abstract.

Blanchet, FP. Moris, A. Nikolic, DS. Cardinaud, S. Stalder, R. Garcia, E. Dinkins, C. Leuba, F. Wu, L. Schwartz, O. Deretic, V. Piguet, V. (2010) Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity May 28;32(5):654-69.Abstract

Brandler, S. Lepelley, A. Desdouits, M. Guivel-Benhassine, F. Ceccaldi, P.E. Lévy, Y. Schwartz, O. Moris, A. (2010) Preclinical Studies of a Modified Vaccinia Virus Ankara-Based HIV Candidate Vaccine : Antigen Presentation and Antiviral Effect.
Journal of Virology May 2010, p 5314-5328. Abstract.

Schilte, C. Couderc, T. Chretien, F. Sourisseau, M. Gangneux, N. Guivel-Benhassine, F. Kraxner, A. Tschopp, J. Higgs, S. Michault, A. Arenzana-Saisdedos, F. Colonna, M. Peduto, L. Schwartz, O. Lecuit, M. Albert, ML. (2010) Type I IFN controls chikungunya virus via its action on nonhematopoietic cells.
Journal of Experimental Medicine March 24, vol 207, n° 2, 429-441.Abstract.

Casartelli, N. Guivel-Benhassine, F. Bouziat, R. Brandler, S. Schwartz, O. Moris, A. (2010) The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells.
Journal of Experimental Medicine Jan 18;207(1):39-49. Abstract.

Nobile, C. Rudnicka, D. Hasan, M. Aulner, N. Porrot, F. Machu, C. Renaud, O. Prévost, MC. Hivroz, C. Schwartz, O. Sol-Foulon, N. (2010) HIV-1 Nef inhibits ruffles, induces filopodia and modulates migration of intected lymphocytes.
Journal of Virology March 24, vol 84, 2282-2293. Abstract.





Rudnicka, D. Schwartz, O. ( 2009) Intrusive HIV-1 infected cells.
Nature Immunology Sept 10 (9):933-4. Abstract.

Vendrame, D. Sourisseau, M. Perrin, V.Schwartz, O. Mammano, F. (2009) Partial inhibition of HIV replication by Type-I Interferons : Impact of Cell-to-Cell viral transfer.
Journal of Virology Oct.83 (20) 10527-37. Abstract.

Fausther-Bovendo, H. Sol-Foulon, N. Agut, H. Schwartz, O. Debré, P. Vieillard, V. (2009)  HIV escape from NK cytotoxicity : Nef inhibits NKp44L expression on CD4 T cells.
AIDS Jun 1 ; 23(9):1077-87. Abstract

Rudnicka, D. Feldmann, J. Porrot, F. Wietgrefe, S. Guadagnini, S. Prevost, MC.  Estaquier, J. Haase, A. Sol-Foulon, N. Schwartz, O. (2009) Simultaneous HIV Cell-to-Cell transmision to multiple targets through polysynapses. Journal of Virology  Jun ; 83(12):6234-46 Abstract

Guerbois, M. Moris, A. Combredet, C. Najburg, V.  Ruffie, C. Fevrier,  M. Cayet,  N. Brandler, S. Schwartz, O. and Tangy F. (2009)  Live attenuated measles vaccine expressing HIV-1 gag virus like particles covered with gp160DeltaV1V2 is strangly immunogenic.
Virology May 25 ; 388(1) : 191-203.  Abstract

Garcia, J.M. Gao, A. P.L, He. Choi, J. Tang, W. Bruzzone, R. Schwartz, O. Naya, H. Nan, FJ.  Li, J. Altmeyer,  R. Zuo, JP. (2009) High-throughput screening using pseudotyped lentiviral particles : a strategy for the identification of HIV-1 inhibitors in a cell-based assay.
Antiviral Res.  Mar ; 81 (3):239-47.  Abstract



Dorival, C. Brizzi, F. Lelièvre, JD. Sol-Foulon, N. Six, E. Henry, A. André-Schmutz, I. Cavazzana-Calvo, M. Coulombel, L. Estaquier, J. Schwartz, O. Lévy, Y. (2008)  HIV-1 Nef protein expression in human CD34+ progenitors impairs the differentiation of an early T/NK cell precursor.
Jul 20;377(1):207-15. Abstract

Zhang, P. M. Skurnik, S.  Zhang, S. Schwartz, O. Kalyanasundaram, R.  Bulgheresi, S.He, J. J. D. Klena, J. Hinnebusch, and Chen, T. (2008)  Human DC-SIGN (CD209) is a receptor for Yersinia pestis that promotes phagocytosis by dendritic cells.
Infection & Immunity May;76(5):2070-9. Abstract



Sourisseau, M., Sol-Foulon, N., Porrot, F., Blanchet, F. and Schwartz, O. (2007) Inefficient human immunodeficiency virus replication in mobile lymphocytes.
Journal of Virology 81, 1000-1012 Abstract

Sol-Foulon, N., Sourisseau, M., Porrot, F., Thoulouze, M.I., Trouillet, C., Nobile, C., Blanchet, F., di Bartolo, V., Noraz, N., Taylor, N., Alcover, A., Hivroz, C. and Schwartz, O. (2007) ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation.
EMBO J, 26, 516-526. Abstract

Schwartz, O. (2007) News & Views : Langerhans cells lap up HIV.
Nature Medicine, 13, 245-6. Abstract

Fackler, O., Alcover, A. and Schwartz, O. (2007) Modulation of the immunological synapse : a key to HIV-1 pathogenesis ? Nat. Rev. Immunol., 7, 310-7. Abstract

Hodges, A., Sharrocks, K., Edelmann, M., Baban, D., Moris, A., Schwartz, O., Drakesmith, H., Davies, K., Kessler, B., McMichael, A. and A. Simmons. 2007. Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication.
Nature Immunology., 8, 569-77.Abstract

di Bartolo, V., Montagne, B., Salek, M., Jungwirth, B., Carrette, F., Fourtane, J., Sol-Foulon, N., Michel, F., Schwartz, O., D.Lehmann, W. and Acuto, O. (2007) A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76.
Journal of Experimental Medicine., 204, 681-91. Abstract

Sourisseau, M., C. Schilte, N. Casartelli, C. Trouillet, F. Guivel-Benhassine, D. Rudnicka, N. Sol-Foulon, K. L. Roux, M. C. Prevost, H. Fsihi, M. P. Frenkiel, F. Blanchet, P. V. Afonso, P. E. Ceccaldi, S. Ozden, A. Gessain, I. Schuffenecker, B. Verhasselt, A. Zamborlini, A. Saib, F. A. Rey, F. Arenzana-Seisdedos, P. Despres, A. Michault, M. L. Albert, and O. Schwartz. 2007. Characterization of Reemerging Chikungunya Virus.
PLoS Pathog 3:e89. Abstract

Jouve, M., N. Sol-Foulon, S. Watson, O. Schwartz, and P. Benaroch. 2007. HIV-1 Buds and Accumulates in "Nonacidic" Endosomes of Macrophages.
Cell Host and Microbe 2:85-95.Abstract

Hoeffel, G., A. C. Ripoche, D. Matheoud, M. Nascimbeni, N. Escriou, P. Lebon, F. Heshmati, J. G. Guillet, M. Gannagé, S. Caillat-Zucman, N. Casartelli, O. Schwartz, H. De la Salle, D. Hanau, A. Hosmalin, and C. Maranon. 2007. Antigen Crosspresentation by Human Plasmacytoid Dendritic Cells. Immunity 27:1-12. Abstract

Ozden, S., M. Huerre, J. P. Riviere, L. L. Coffey, P. V. Afonso, V. Mouly, J. de Monredon, J. C. Roger, M. El Amrani, J. L. Yvin, M. C. Jaffar, M. P. Frenkiel, M. Sourisseau, O. Schwartz, G. Butler-Browne, P. Despres, A. Gessain, and P. E. Ceccaldi. 2007. Human muscle satellite cells as targets of chikungunya virus infection. PLoS ONE 2:e527.Abstract

Py, B., J. Bouchet, G. Jacquot, N. Sol-Foulon, S. Basmaciogullari, O. Schwartz, M. Biard-Piechaczyk, and S. Benichou. 2007. The Siva protein is a novel intracellular ligand of the CD4 receptor that promotes HIV-1 envelope-induced apoptosis in T-lymphoid cells.
Apoptosis Oct 12 (10) 1879-92 .Abstract

Brandler S, Lucas-Hourani M, Moris A, Frenkiel M.P., Combredet C., Février M., Bedouelle H., Schwartz O., Desprès P., and Tangy F. 2007. « Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus »,
PLoS Negl Trop Dis 1(3): e96. Abstract





Delebecque F, Suspène R, Calattini S, Casartelli N, Saïb A, Froment A, Wain-Hobson S, Gessain A, Vartanian J.P, Schwartz O. Restriction of Foamy Viruses by APOBEC cytidine deaminases.
Journal of Virology 2006 ; 80 : 605-14.Abstract

Moris, A., Pajot, A., Blanchet, F., Guivel-Benhassine, F., Salcedo, M., and Schwartz, O. (2006). Dendritic cells and HIV-specific CD4+ T cells: HIV antigen presentation, T cell activation, viral transfer.
Blood. 108(5):1643-51. Abstract

Thoulouze, M. I., Sol-Foulon, N., Blanchet, F., Dautry-Varsat, A., Schwartz, O., and Alcover, A. (2006). Human Immunodeficiency Virus Type-1 Infection Impairs the Formation of the Immunological Synapse. Immunity 24, 547-561. Abstract

Esnault, C., Millet, J., Schwartz, O., and Heidmann, T. (2006). Dual inhibitory effects of APOBEC family proteins on retrotransposition of mammalian endogenous retroviruses.
Nucleic Acids Res 34, 1522-1531. Abstract

Fackler, O. T., Moris, A., Tibroni, N., Giese, S. I., Glass, B., Schwartz, O., and Krausslich, H. G. (2006). Functional characterization of HIV-1 Nef mutants in the context of viral infection. Virology. 351(2) :322-39. Abstract

Rybner-Barnier, C., Jacquemot, C., Cuche, C., Dore, G., Majlessi, L., Gabellec, M. M., Moris, A., Schwartz, O., Di Santo, J., Cumano, A., et al. (2006). Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells.
Journal of  Virology 80, 4656-4663. Abstract

Ceccaldi, P. E., Delebecque, F., Prevost, M. C., Moris, A., Abastado, J. P., Gessain, A., Schwartz, O., and Ozden, S. (2006). DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus Type 1-infected cells. Journal of Virology 80, 4771-4780. Abstract

Zhang, P., Schwartz, O., Pantelic, M., Li, G., Knazze, Q., Nobile, C., Radovich, M., He, J., Hong, S. C., Klena, J., and Chen, T. DC-SIGN (CD209) recognition of Neisseria gonorrhoeae is circumvented by lipooligosaccharide variation. J Leukoc Biol. 2006, 79 : 731-8.Abstract

Muratori, C., D’Aloja, P., Superti, F., Tinari, A., Sol-Foulon, N., Sparacio, S., Bosch, V., Schwartz, O. and Federico, M. (2006) Generation and characterization of a stable cell population releasing fluorescent HIV-1-based Virus Like Particles in an inducible way.
BMC Biotechnol, 6, 52. Abstract


Esnault C, Heidmann O, Delebecque F, Dewannieux M, Ribet D, Hance AJ, Heidmann T, Schwartz O. APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.
Nature. 2005;433:430-433. Abstract

Nobile C, Petit C, Moris A, Skrabal K, Abastado JP, Mammano F, Schwartz, O. Covert HIV replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes.
Journal of  Virology  2005 ; 79 :5386-5399.Abstract

Tailleux L, Pham-Thi Nhan, Bergeron-Lafaurie, A, Herrmann J.L, Charles P, Schwartz O, Scheinmann P, Lagrange H, Philippe, de Blic, J., Tazi A, Gicquel B, Neyrolles O. DC-SIGN Induction in Alveolar Macrophages Defines a Priviliged Target Host Cell Population for Mycobacteria in Patients with Tuberculosis. PloS Medicine, 2005 ; 2 : e381.Abstract

Klena, J., Zhang, P., Schwartz, O., Hull, S., and Chen, T. The core lipopolysaccharide of Escherichia coli is a ligand for the dendritic-cell-specific intercellular adhesion molecule nonintegrin CD209 receptor.
Journal of  Bacteriology  2005 ;187, 1710-1715.Abstract

Mahieux, R., Suspene, R., Delebecque, F., Henry, M., Schwartz, O., Wain-Hobson, S., and Vartanian, J. P. Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases.
Journal of  General Virology 2005 ; 86, 2489-2494.Abstract

Pitarque, S., Herrmann, J. L., Duteyrat, J. L., Jackson, M., Stewart, G. R., Lecointe, F., Payre, B., Schwartz, O., Young, D. B., Marchal, G., Lagrange, P. H. Puzo, G., Gicquel, B., Nigou, J.
Neyrolles, O. Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity.
Biochemestry  Journal  2005 . 392, 615-624.Abstract



Moris A, Nobile C, Buseyne F, Porrot F, Abastado JP, Schwartz O. DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation.
Blood. 2004 ;103:2648-2654. Abstract

Schwartz O. Cell of the month. Dendritic cell sensing a lymphocyte.
Nature Cell Biology. 2004;6:188 & Nat Rev Mol Cell Biol. 2004; 5:175 Abstract

Sol-Foulon N, Esnault C, Percherancier Y, Porrot F, Metais-Cunha P, Bachelerie F, Schwartz O. The effects of HIV-1 Nef on CD4 surface expression and viral infectivity in lymphoid cells are independent of rafts. J Biol Chem. 2004 ; 279 :31398-408.Abstract

Cardinaud S, Moris A, Fevrier M, Rohrlich PS, Weiss L, Langlade-Demoyen P, Lemonnier FA, Schwartz O, Habel A. Identification of Cryptic MHC I-restricted Epitopes Encoded by HIV-1 Alternative Reading Frames. Journal of Experimental Medicine 2004;199:1053-1063.Abstract

Ploquin MJ, Diop OM, Sol-Foulon N, Mortara L, Faye A, Soares MA, Nerrienet E, Le Grand R, Van Kooyk Y, Amara A, Schwartz O, Barre-Sinoussi F, Muller-Trutwin MC. DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm. Journal of Virology 2004;78:798-810.Abstract

Schwartz O. HIV-1, un virus très Vif! Médecine/Sciences. 2004;20:139-141.

Lozach PY, Nobile C, Altmeyer R, Schwartz O. DC-SIGN: un récepteur à large spectre.
Virologie. 2004 ; 8 :113-124.


Nobile C, Moris A, Porrot F, Sol-Foulon N, Schwartz O. Inhibition of Human Immunodeficiency Virus Type 1 Env-Mediated Fusion by DC-SIGN.
Journal of  Virology  2003;77:5313-5323.Abstract

Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B, Neyrolles O. DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells.
Journal of Experimental Medicine  2003;197:121-127.Abstract

Navarro-Sanchez E, Altmeyer R, Amara A, Schwartz O, Fieschi F, Virelizier JL, Arenzana-Seisdedos F, Despres P. Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses.
EMBO Rep. 2003;4:723-728.Abstract

Violot S, Hong SS, Rakotobe D, Petit C, Gay B, Moreau K, Billaud G, Priet S, Sire J, Schwartz O, Mouscadet JF, Boulanger P. The human polycomb group EED protein interacts with the integrase of human immunodeficiency virus type 1.
Journal of  Virology  2003;77:12507-12522.Abstract

Lozach PY, Lortat-Jacob H, De Lacroix De Lavalette A, Staropoli I, Foung S, Amara A, Houles C, Fieschi F, Schwartz O, Virelizier JL, Arenzana-Seisdedos F, Altmeyer R. DC-SIGN and L-SIGN Are High Affinity Binding Receptors for Hepatitis C Virus Glycoprotein E2.
J Biol Chem. 2003;278:20358-20366.Abstract


Sol-Foulon N, Moris A, Nobile C, Boccaccio C, Engering A, Abastado JP, Heard JM, van Kooyk Y, Schwartz O. HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread. Immunity. 2002;16:145-155.Abstract

Marsac D, Loirat D, Petit C, Schwartz O, Michel ML. Enhanced presentation of major histocompatibility complex class I-restricted human immunodeficiency virus type 1 (HIV-1) Gag-specific epitopes after DNA immunization with vectors coding for vesicular stomatitis virus glycoprotein-pseudotyped HIV-1 Gag particles.
Journal of  Virology 2002;76:7544-7553.Abstract


Buseyne F, Le Gall S, Boccaccio C, Abastado JP, Lifson JD, Arthur LO, Riviere Y, Heard JM, Schwartz O. MHC-I-restricted presentation of HIV-1 virion antigens without viral replication.
Nature Medicine. 2001;7:344-349.Abstract

Maréchal V, Prevost MC, Petit C, Perret E, Heard JM, Schwartz O. Human Immunodeficiency Virus type 1 entry into macrophages mediated by macropinocytosis.
Journal of Virology 2001;75:11166-11177.Abstract

Stumptner-Cuvelette P, Morchoisne S, Dugast M, Le Gall S, Raposo G, Schwartz O, Benaroch P. HIV-1 Nef impairs MHC class II antigen presentation and surface expression.
Proc. Natl. Acad. Sci. (USA). 2001;98:12144-12149.Abstract

Petit C, Buseyne F, Boccaccio C, Abastado JP, Heard JM, Schwartz O. Nef is required for efficient HIV-1 replication in cocultures of dendritic cells and lymphocytes.
Virology. 2001, 286, 225-236.Abstract

 Janvier K, Craig H, Le Gall S, Benarous R, Guatelli J, Schwartz O, Benichou S. Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP.
Journal of  Virology 2001;75:3971-3976.Abstract

Desmaris N, Bosch A, Salaun C, Petit C, Prevost MC, Tordo N, Perrin P, Schwartz O, de Rocquigny H, Heard JM. Production and neurotropism of lentivirus vectors pseudotyped with lyssavirus envelope glycoproteins. Mol Ther. 2001;4:149-156.Abstract



Updated on 07/07/2014

Practical Information

We are based at the Pasteur Institute in Paris (France) 28, rue du Dr Roux, close to the "Pasteur" and "Volontaires" metro stations.

Our lab is located on the 4th floor of the Lwoff building (building n° 22 on the map below). 



How to get to Pasteur Institute

Web links


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