The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
The major achievements on the last five years are the following: (1) the role of dermal cells in the pathogenicity of flaviviruses, (2) the role of dynein light chain Tctex-1 in the late stages of flavivirus replication, (3) the role of the IFN-inducible 2',5'-Oligoadenylate Synthetases (OAS) in the host cell defences against arboviruses, (4) identification of viral determinants that enable subversion of WN, YF and CHIK viruses towards OAS, (5) development of immunotherapeutic tools as well as dengue, West Nile and Chikungunya vaccines using non-replicative lentivirus vector and live-attenuated measles virus, and (6) development of innovative biotechnologies for improving molecular detection of arboviruses and serodiagnosis of virus-related diseases.
• Molecular Virology
• Interactions virus/host-cell (vertebrates and invertebrates)
• Viral pathogenicity towards antiviral innate immunity
• Pathogenesis of arbovirus infection
• Development of new diagnosis tools
• Development of candidate vaccines against arboviruses
The FHMI lab is sharing with the CIBU (JC. Manugerra) and Antiviral Strategies lab (N. Tordo), the WHO Collaborating Centre for Reference and Research on Arboviruses and Viral Haemorrhagic Fevers and the OIE Collaborating Centre for Rift Valley Fever and Crimean-Congo Hemorrhagic Fever viruses at the Institut Pasteur.
The FHMI team is widely involved in the teaching of PhD students in virology and training of medical virologists or clinicians in France and Europe (EU FP-7 program EPISOUTH Plus) in link with the International Network of Instituts Pasteur.
Training experiences 2007-2012
Master students 5 completed
PhD students 4 completed
Post-doctoral scientists 5 completed 2 current
Grant income in 2012
• European Program FP_7-Health EUROWESTNILE) "European West Nile collaborative research project"
• European Program FP-7-Health EMPERIE "European Management Platform for Emerging and Reemerging Infectious disease Entities"
• European Program FP-7-Health PREDEMICS "Prediction and Prevention of Emerging Zoonotic Viruses with Pandemic Potential using Multidisciplinary Approaches"
• French National Agency of Research’s grant ARBOAS "Deciphering the role of Human OAS gene family in the pathogenesis of arbovirus infection"
• French National Agency of Research’s grant KerARBO "Role of salivary factors of Aedes albopictus in the permissiveness of human skin cells to Dengue and Chikungunya viruses"