Lab members

abfailloux.jpgANNA-BELLA FAILLOUX, PhD

 

GROUP LEADER
anna-bella.failloux@pasteur.fr

 

Current Position

Principal Investigator

Chef de Laboratoire

Arboviruses and Insect Vectors

 

Background

D.E.A. (Master), 1988

Ecology, University of Toulouse III (Paul Sabatier), France

 

Medical Entomology Course, Institut Pasteur, Paris, France, 1988

 

Ph.D., 1994

Ecophysiology and Population dynamics of terrestral invertebrates, University of Paris XI, France (Nicole Pasteur)

 

Postdoctoral Fellow, 1994-1996

Institut Pasteur, Ecology of Vectorial Systems (François Rodhain)

 

H.D.R., 2000

University of Paris XII, France

 

Publications


marie-vazeille.jpgMARIE VAZEILLE, PhD

 

ENGINEER

marie.vazeille@pasteur.fr

 

Current Position

My project concerns the emergence of the mutated strain of CHIKV (E1-A226V) during the outbreak of 2011 in Congo (Brazzaville) in relation with the recent introduction and expansion of Ae. albopictus. As stated in East Africa where this mutation has emerged leading to a better transmission by Ae. albopictus, is this scenario applicable to West Africa?

 

Ph.D., 1987

Genetics, University of Clermont-Ferrand II (Blaise Pascal), France

 

Medical Entomology Course, Institut Pasteur, Paris, France, 1988

 

Publications

 


 

laurence.jpgLAURENCE MOUSSON

 

TECHNICIAN

laurence.mousson@pasteur.fr

 

Current Position

My project is part of the FP7 DenFree project. The tasks where I am involved aim to examine the role of mosquito vectors in dengue emergence, with special emphasis on the European context. I will be implicated in evaluating the ability of European Aedes albopictus to transmit imported DENV strains (originated from DEN endemic regions, Thailand and Cambodia) and in identifying viral genetic changes after experimental alternating cycling to enhance potential of Ae. albopictus from southern France to transmit imported DEN strains from Southeast Asia.

 

 

Background

BTS, 1985

Ecole Technique Supérieure du Laboratoire, Paris, France

 

 

Publications

 


 

karima-zouache-2.jpgKARIMA ZOUACHE, PhD

 

POST-DOCTORAL FELLOW

karima.zouache@pasteur.fr

 

Current Position

My project is part of the FP7 Vectorie project on surveillance of two arthropod-borne diseases, West-Nile and Chikungunya, in Europe. Our laboratory is involved in defining the vector competence of Ae. albopictus mosquitoes from different European countries for CHIK virus at low temperatures. I am responsible of three main tasks which are: (i) experimentally challenges of field-collected European populations of Ae. albopictus (France, Italy, Montenegro) with different CHIKV isolates; (ii) evaluation of mosquito thermo-preference and (iii) effects of temperature on gene expression in temperate Ae. albopictus infected by different strains of CHIKV and submitted to thermal stress, using a transcriptomic approach provided by the technology of high throughput RNA sequencing.

 

 

Background

D.E.A. (Master), 2006

Microbial Ecology, University of Lyon I (Claude Bernard), France

 

Ph.D., 2010

Microbial Ecology, University of Lyon I (Claude Bernard), France

 

Publications

  


 

faustine_louis.jpgFAUSTINE LOUIS, PhD

 

POST-DOCTORAL FELLOW

 

faustine.louis@pasteur.fr

           

Current Position

My project is part of the EMIDA project and concerns the risk for European mosquitoes to become a vector of the Rift Valley fever virus. To evaluate this risk, we have to investigate (i) the molecular identification of RVFV vectors (Ae. vexans complex and Cx. pipiens complex) with special focus on European counterparts of tropical mosquitoes species through the use of molecular tools and estimate the abundance and dynamics of potential RVFV vectors in Camargue (France); (ii) characterize the competence of potential European RVFV vectors in comparison with their African counterparts, and (iii) investigate through in vivo experiments if RVFV can be adapted to European mosquitoes.

 

Background

Master, 2008

Infectiologie cellulaire et moléculaire , vaccinologie, Université François Rabelais, Tours, France

Ph.D., 2013

Science de la vie et de la santé, Université François Rabelais, Tours, France

 

Publications

Louis F, Bézier A, Periquet G, Ferras C, Drezen JM, Dupuy C, 2013. The bracovirus genome of the parasitoid wasp Cotesia congregata is amplified within 13 replication units, including sequences not packaged in the particles. J Virol 87(17) : 9649-60.

Bézier A, Louis F, Jancek S, Periquet G, Thézé J, Gyapay G, Musset K, Lesobre J, Lenoble P, Dupuy C, Gundersen-Rindal D, Herniou EA, Drezen JM, 2013. Functional endogenous viral elements in the genome of the parasitoid wasp Cotesia congregata: insights into the evolutionary dynamics of bracoviruses. Philos Trans R Soc Lond B Biol Sci 368 (1626) : 20130047.

Dupuy C, Periquet G, Serbielle C, Bézier A, Louis F, Drezen JM, 2011. Transfer of a chromosomal Maverick to endogenous bracovirus in a parasitoid wasp. Genetica 139(4):489-496.

 


 

jocelyne-alexandre.jpg

 

JOCELYNE ALEXANDRE

 

Agent de Laboratoire

jocelyne.alexandre@pasteur.fr

 

Current Position

I am in charge of the maintenance of the insectaries.

 

 

 

 

 

 

 

anubis.jpgANUBIS VEGA-RUA
           

PhD STUDENT

 

anubis.vega-rua@pasteur.fr

 

Current Position

 

My PhD project aims to analyze the risk for CHIKV to emerge in Latin America, a continent where the typical CHIKV vectors Ae. aegypti and Ae. albopictus are present in high densities, and where several CHIKV importation cases have been reported. Until now, local CHIKV transmission has never been reported in Latin America. To assess this risk, I will: (i) evaluate the vector competence of different field-collected Aedes albopictus from Latin America to transmit several genotypes of CHIKV, (ii) study CHIKV evolution and adaptation to Latin American vectors using in vitro and in vivo systems and, (iii) trace the evolutionary history of Aedes albopictus using phylogenetic approaches.

 

Background

D.E.A. (Master), 2011

Genetic and biodiversity managment, University Pierre and Marie Curie / Institut Pasteur, Paris, France

 

Ph.D. Student, 2012-2015

University Pierre and Marie Curie / Institut Pasteur, Paris, France.

 


 

azdeen.jpeg

Azdeen GOLAMAULLY

 

Master student

azdeen.golamaully@pasteur.fr

 

My project aims to study the adaptation of chikungunya virus (CHIKV)to Aedes albopictus mosquito at low temperature. I will first use in vitro system to obtain thermo-sensitive variants of CHIKV.  Then, we will test the fitness of the virus variants obtained at different temperatures using in vitro (mammals and insects cells) and in vivo (i.e. Ae. albopictus populations) systems.

 

Background

 

Master 2, 2013-2014

Virologie Fondamentale, Institut Pasteur (University Pierre et Marie Curie)

 

Master 1, 2013

Biologie Moléculaire et Cellulaire (University Pierre et Marie Curie)

 


 

henri_jupille.jpg

Henri JUPILLE, PhD

 

Post-doctoral fellow

henri.jupille@pasteur.fr

 

Current Position

My research is a part of the European Union’s DENFREE project. With the recent autochthonous cases of dengue in France (2010), Croatia (2010) and in the Portuguese island of Madeira (2012), dengue has arrived in Europe. As an arbovirus, dengue virus (DENV) requires replication in both a vertebrate host and insect vector, and interactions between these two disparate hosts within a permissive environment determine the outcome of transmission. My main objectives are: (i) to select a DENV more adapted to be transmitted by European Aedes albopictus using serial passages, and (ii) to generate molecular clones of these adapted strains, allowing me to characterize the molecular mechanisms behind this adaptation. These studies will provide unique insights into viral-vector interactions and their impact on fitness in mammalian systems.

 

 

Background

 

Ph.D., 2013

Microbiology, University of Colorado Anschutz Medical Campus, Aurora Colorado, USA

 

Bachelor of Science, 2005

Biology, Colorado Mesa University, Grand Junction, Colorado, USA

 


FORMER MEMBERS

 

ricardo.jpgRICARDO LOURENCO-DE-OLIVEIRA

 

Visiting scientist

lourenco@ioc.fiocruz.br

 

 

 

 

 

camilo.jpgCAMILO ARIAS-GOETA, PhD student

 

PhD student

camilo.arias.goeta@gmail.com

 

 

 

 

 

ilaria.jpgILARIA CASTELI, PhD

 

POST-DOCTORAL FELLOW

castelli.ilaria84@gmail.com

 

 

 

Updated on 25/04/2014

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