Lab members

abfailloux.jpgANNA-BELLA FAILLOUX, PhD




Current Position

Principal Investigator

Chef de Laboratoire

Arboviruses and Insect Vectors



D.E.A. (Master), 1988

Ecology, University of Toulouse III (Paul Sabatier), France


Medical Entomology Course, Institut Pasteur, Paris, France, 1988


Ph.D., 1994

Ecophysiology and Population dynamics of terrestral invertebrates, University of Paris XI, France (Nicole Pasteur)


Postdoctoral Fellow, 1994-1996

Institut Pasteur, Ecology of Vectorial Systems (François Rodhain)


H.D.R., 2000

University of Paris XII, France



marie-vazeille.jpgMARIE VAZEILLE, PhD




Current Position

My project concerns the emergence of the mutated strain of CHIKV (E1-A226V) during the outbreak of 2011 in Congo (Brazzaville) in relation with the recent introduction and expansion of Ae. albopictus. As stated in East Africa where this mutation has emerged leading to a better transmission by Ae. albopictus, is this scenario applicable to West Africa?


Ph.D., 1987

Genetics, University of Clermont-Ferrand II (Blaise Pascal), France


Medical Entomology Course, Institut Pasteur, Paris, France, 1988









Current Position

My project is part of the FP7 DenFree project. The tasks where I am involved aim to examine the role of mosquito vectors in dengue emergence, with special emphasis on the European context. I will be implicated in evaluating the ability of European Aedes albopictus to transmit imported DENV strains (originated from DEN endemic regions, Thailand and Cambodia) and in identifying viral genetic changes after experimental alternating cycling to enhance potential of Ae. albopictus from southern France to transmit imported DEN strains from Southeast Asia.




BTS, 1985

Ecole Technique Supérieure du Laboratoire, Paris, France






karima-zouache-2.jpgKARIMA ZOUACHE, PhD




Current Position

My project is part of the FP7 Vectorie project on surveillance of two arthropod-borne diseases, West-Nile and Chikungunya, in Europe. Our laboratory is involved in defining the vector competence of Ae. albopictus mosquitoes from different European countries for CHIK virus at low temperatures. I am responsible of three main tasks which are: (i) experimentally challenges of field-collected European populations of Ae. albopictus (France, Italy, Montenegro) with different CHIKV isolates; (ii) evaluation of mosquito thermo-preference and (iii) effects of temperature on gene expression in temperate Ae. albopictus infected by different strains of CHIKV and submitted to thermal stress, using a transcriptomic approach provided by the technology of high throughput RNA sequencing.




D.E.A. (Master), 2006

Microbial Ecology, University of Lyon I (Claude Bernard), France


Ph.D., 2010

Microbial Ecology, University of Lyon I (Claude Bernard), France





faustine_louis.jpgFAUSTINE LOUIS, PhD




Current Position

My project is part of the EMIDA project and concerns the risk for European mosquitoes to become a vector of the Rift Valley fever virus. To evaluate this risk, we have to investigate (i) the molecular identification of RVFV vectors (Ae. vexans complex and Cx. pipiens complex) with special focus on European counterparts of tropical mosquitoes species through the use of molecular tools and estimate the abundance and dynamics of potential RVFV vectors in Camargue (France); (ii) characterize the competence of potential European RVFV vectors in comparison with their African counterparts, and (iii) investigate through in vivo experiments if RVFV can be adapted to European mosquitoes.



Master, 2008

Infectiologie cellulaire et moléculaire , vaccinologie, Université François Rabelais, Tours, France

Ph.D., 2013

Science de la vie et de la santé, Université François Rabelais, Tours, France



Louis F, Bézier A, Periquet G, Ferras C, Drezen JM, Dupuy C, 2013. The bracovirus genome of the parasitoid wasp Cotesia congregata is amplified within 13 replication units, including sequences not packaged in the particles. J Virol 87(17) : 9649-60.

Bézier A, Louis F, Jancek S, Periquet G, Thézé J, Gyapay G, Musset K, Lesobre J, Lenoble P, Dupuy C, Gundersen-Rindal D, Herniou EA, Drezen JM, 2013. Functional endogenous viral elements in the genome of the parasitoid wasp Cotesia congregata: insights into the evolutionary dynamics of bracoviruses. Philos Trans R Soc Lond B Biol Sci 368 (1626) : 20130047.

Dupuy C, Periquet G, Serbielle C, Bézier A, Louis F, Drezen JM, 2011. Transfer of a chromosomal Maverick to endogenous bracovirus in a parasitoid wasp. Genetica 139(4):489-496.







Agent de Laboratoire


Current Position

I am in charge of the maintenance of the insectaries.











Current Position


My PhD project aims to analyze the risk for CHIKV to emerge in Latin America, a continent where the typical CHIKV vectors Ae. aegypti and Ae. albopictus are present in high densities, and where several CHIKV importation cases have been reported. Until now, local CHIKV transmission has never been reported in Latin America. To assess this risk, I will: (i) evaluate the vector competence of different field-collected Aedes albopictus from Latin America to transmit several genotypes of CHIKV, (ii) study CHIKV evolution and adaptation to Latin American vectors using in vitro and in vivo systems and, (iii) trace the evolutionary history of Aedes albopictus using phylogenetic approaches.



D.E.A. (Master), 2011

Genetic and biodiversity managment, University Pierre and Marie Curie / Institut Pasteur, Paris, France


Ph.D. Student, 2012-2015

University Pierre and Marie Curie / Institut Pasteur, Paris, France.






Master student


My project aims to study the adaptation of chikungunya virus (CHIKV)to Aedes albopictus mosquito at low temperature. I will first use in vitro system to obtain thermo-sensitive variants of CHIKV.  Then, we will test the fitness of the virus variants obtained at different temperatures using in vitro (mammals and insects cells) and in vivo (i.e. Ae. albopictus populations) systems.




Master 2, 2013-2014

Virologie Fondamentale, Institut Pasteur (University Pierre et Marie Curie)


Master 1, 2013

Biologie Moléculaire et Cellulaire (University Pierre et Marie Curie)






Post-doctoral fellow


Current Position

My research is a part of the European Union’s DENFREE project. With the recent autochthonous cases of dengue in France (2010), Croatia (2010) and in the Portuguese island of Madeira (2012), dengue has arrived in Europe. As an arbovirus, dengue virus (DENV) requires replication in both a vertebrate host and insect vector, and interactions between these two disparate hosts within a permissive environment determine the outcome of transmission. My main objectives are: (i) to select a DENV more adapted to be transmitted by European Aedes albopictus using serial passages, and (ii) to generate molecular clones of these adapted strains, allowing me to characterize the molecular mechanisms behind this adaptation. These studies will provide unique insights into viral-vector interactions and their impact on fitness in mammalian systems.





Ph.D., 2013

Microbiology, University of Colorado Anschutz Medical Campus, Aurora Colorado, USA


Bachelor of Science, 2005

Biology, Colorado Mesa University, Grand Junction, Colorado, USA






Visiting scientist






camilo.jpgCAMILO ARIAS-GOETA, PhD student


PhD student












Updated on 25/04/2014


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