The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
Laurenceau R, Péhau-Arnaudet G, Baconnais S, Gault J, Malosse C, Dujeancourt A, Campo N, Chamot-Rooke J, Le Cam E, Claverys JP, Fronzes R. PLoS Pathog. 2013 Jun;9(6):e1003473.
Rivera-Calzada A, Fronzes R, Savva CG, Chandran V, Lian PW, Laeremans T, Pardon E, Steyaert J, Remaut H, Waksman G, Orlova EV.
EMBO J. 2013 Apr 17;32(8):1195-204.
Baranova E, FronzesR, Garcia-Pino A, Van Gerven N, Papapostolou D, Péhau-Arnaudet G, Pardon E, Steyaert J, Howorka S, Remaut H.
Nature. 2012 Jul 5;487(7405):119-22.
Waksman G. and Fronzes R.
Molecular architecture of bacterial type IV secretion systems Trends in Biochemical Sciences, 2010 Dec;35(12):691-8
Rego AT, Fronzes R, Waksman G. SnapShot: Bacterial Appendages II. Cell. 2010 Jan 22;140(2):294-294.e1.
Rego AT, Fronzes R, Waksman G. SnapShot: Bacterial Appendages I. Cell. 2010 Jan 8;140(1):162
Chandran V*., Fronzes R.* , Duquerroy S., Cronin N., Navaza J., Waksman G.
*share equal contribution
Crystal structure of the outer membrane complex of a type IV secretion system Nature. 2009 Dec 24;462(7276):1011-5. Epub 2009 Nov 29.
Fronzes R., Christie P.J. and Waksman G.
The structural biology of type IV secretion systems. Nat Rev Microbiol. 2009 Oct;7(10):703-14.
Durand E, Verger D, Rêgo AT, Chandran V, Meng G, Fronzes R., Waksman G.
Structural Biology of Bacterial Secretion Systems in Gram-negative Pathogens- Potential for New Drug Targets. Infect Disord Drug Targets. 2009 Oct 1.
Meng G., Fronzes R., Chandran V., Remaut H. and Waksman G.
Protein oligomerization in the bacterial outer membrane. Mol Membr Biol. 2009 Apr;26(3):136-45.
Fronzes R., Schäfer E., Wang L., Saibil H., Orlova E. and Waksman G.
Structure of a type IV secretion system core complex. Science. 2009 Jan 9;323(5911):266-8.
Backert S., Fronzes R. and Waksman G.
VirB2 and VirB5 proteins: specialized adhesins in bacterial type-IV secretion systems? Trends Microbiol. 2008 Sep;16(9):409-13.
Fronzes R., Remaut H. and Waksman G.
Architectures and biogenesis of non-flagellar protein appendages in Gram-negative bacteria. EMBO J. 2008 Sep 3;27(17):2271-80.
Goyon V. *, Fronzes R.*, Salin B, di-Rago J.P., Velours J. and Brèthes D.
*share equal contribution
Yeast cells depleted in Atp14p fail to assemble Atp6p within the ATP synthase and exhibit altered mitochondrial cristae morphology. J Biol Chem. 2008 Apr 11;283(15):9749-58.
Bayliss, R., Harris R., Coutte L., Monier A., Fronzes R., Christie, P.J, Driscoll P. and Waksman G.
NMR structure of a complex between the VirB9/VirB7 interaction domains of the pKM101 type IV secretion system. Proc Natl Acad Sci U S A, 2007 Jan 30;104(5):1673-8.
Fronzes R., Weimann T., Vaillier J., Velours J. and Brèthes D.
The peripheral stalk participates in the yeast ATP synthase dimerization independently of e and g subunits. Biochemistry. 2006 May 30;45(21):6715-23.
Fronzes R., Chaignepain S., Bathany K., Giraud M.F., Arselin G., Schmitter J.M., Dautant A., Velours J. and Brèthes D.
Topological and functional study of subunit h of the F1Fo ATP synthase complex in yeast Saccharomyces cerevisiae. Biochemistry. 2003 Oct 21;42(41):12038-49.
Envelope spanning secretion systems in Gram-negative bacteria
Matthias J Brunner, Rémi Fronzes, Thomas C Marlovits
Bacterial membranes: Structural and molecular biology, Horizon press, In press