NMR of Biomolecules

Unit Head : Muriel Delepierre

 

Our research is mainly dedicated to understanding the function of bio-macromolecules such as proteins, nucleic acids and oligosaccharides through the study of their structure, interactions and dynamics. To this end, we use NMR, biophysical and biochemical techniques and work in collaboration with various groups from the Institut Pasteur and with laboratories in France and abroad.

 

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The main projects currently being undertaken in our laboratory are:

(i) Structural and functional studies of proteins involved in the active transport of nutrients in bacteria Aspergillus fumigatus;

(ii) The control of neuronal death and survival by the rabies virus glycoprotein;

(iii) PDZ mediated viral perturbation of infected cells signaling pathways;

(iv) Function of whirlin in the mecanoelectric transduction in the internal ear;

(v) Biosynthesis of the fungal cell wall and structural and functional analysis of the RodA hydrophobins from Aspergillus fumigatus conidia.

 

 

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Contact

NMR of Biomolecules
CNRS UMR 3528
Muriel Delepierre

 

Institut Pasteur
28, Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE

Head of the lab : Tel + 33 (0)1 45 68 88 71
Secretary : Tel + 33 (0)1 40 61 37 02
Fax + 33 (0)1 45 68 89 29

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