Statistical and Mathematical Modeling in Biological Applications

The seminar series Statistical and Mathematical Modeling in Biological Applications (SaMMBA) features monthly lectures and discussions with leading modelers in biological sciences. Presentations are in English or French and target an interdisciplinary audience. Seminars are held on the campus of Institut Pasteur. Access is free. However, to enter the campus, one needs a badge that is obtained at the main gate in exchange of a piece of ID (passport, citizen card or driver licence).

 

For additional information about the series, contact the organizers: Pierre-Yves BöelleRomulus BrebanVittoria ColizzaJudith LegrandLulla OpatowskiVirginie SupervieLaura Temime and Elisabeta Vergu. To arrange to meet with an invited speaker, contact the host of that speaker. 

 

 

Next Lecture

 

Carlo Giovanni CAMARDA

 

Modelling Social Contact Data: a smoothing constrained approach

 

Abstract: Mathematical modelling of infectious diseases transmitted by the respiratory or close-contact route (e.g. influenza) is increasingly being used to determine the impact of possible interventions. Several authors have shown that informing mathematical models with social contact data is of great value avoiding making a priori contact assumptions with little or no empirical basis. Moreover, it has also been shown that estimating mixing patterns from social contact data is not without difficulties and model choice is likely to affect the mathematical model outcome substantially. In this paper we present a model for estimating age-specific contact rates from social contact surveys. Specifically we propose a smoothing constrained approach to estimate these contact rates between people of possibly different ages. We use a two-dimensional approach where contact rates are assumed smooth from a cohort perspective as well as from the age distribution of contacts. The proposed method uses a combination of penalized likelihood for rectangular arrays for smoothing the contact rates and linear constraints to ensure reciprocity of contacts. We illustrate our approach using social contact data from a population-based contact survey that has been carried out in Belgium in 2006.

 

Contact: Romulus BREBAN

Tue, June 10th, 2014 

  12 noon -1 pm

Room Jean-Paul Aubert

 


Full Schedule 2013-2014

 

Alun LLOYD

Modeling novel strategies for controlling mosquito-borne diseases

Abstract 

Tue, Sep 24th, 2013 
  12 noon -1 pm 

Joseph DUREAU

 The Public Library of Models: an open source project towards social modeling

Abstract

Tue, Oct 8th, 2013 
  12 noon -1 pm 

Room Jules Bordet 

Julia GOG

Capturing the spread and evolution of influenza A

Abstract

Tue, Nov 5th, 2013 
  12 noon -1 pm 

Véronique THOMAS-VASLIN

Modélisation de la dynamique lymphocytaire T 

Abstract

Tue, Dec 10th, 2013 
  12 noon -1 pm 

Room Jean-Paul Aubert

Bernard
 CAZELLES

Wavelet analysis as a tool for considering non-stationarity in Epidemiology

Abstract

Tue, Jan 7th, 2014 
  12 noon -1 pm 

Room Jean-Paul Aubert

Jeremie GUEDJ

Modeling hepatitis C viral kinetic in the era of direct acting antiviral agents: review and perspectives

Abstract

Tue, Feb 11th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert

Peter WHITE

Tackling TB in the Age of Austerity: ensuring we use novel tools and approaches cost-effectively

Abstract

Tue, Mar 4th, 2014
  12:30 noon -1:30 pm

Room Jean-Paul Aubert  

Aurélien LATOUCHE

Regression modeling of the cumulative incidence function with missing causes of failure

Abstract

Tue, Apr 1st, 2014
  12 noon -1 pm

Room Jean-Paul Aubert 

Aaron KING

How to tell if the honeymoon is over: testing hypotheses about pertussis and its resurgence

Abstract

Tue, May 6th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert 

Carlo Giovanni CAMARDA

Modelling Social Contact Data: a smoothing constrained approach

Abstract

Tue, Jun 10th, 2014
  12 noon -1 pm 

Room Jean-Paul Aubert 
  

 


Full Schedule 2012-2013

 

Aslam ANIS

Cost-effectiveness of diacetylmorphine versus methadone for chronic opioid dependence refractory to treatment

Abstract

Wed, Sep 12th, 2012 
  12 noon -1 pm 

Virginie SUPERVIE

Epidémie cachée du VIH : Que peut-on apprendre des modèles
mathématiques ?

Abstract

Tue, Oct 16th, 2012 
  12 noon -1 pm 

Olivier TENAILLON

Adaptive constraints at the genomic and genic level in E. coli 

Abstract

Tue, Nov 6th, 2012 
  12 noon -1 pm 

Lulla OPATOWSKI 

Trends of pneumococcal meningitis: unmasking the role of winter viruses and antimicrobial drugs 

Abstract 

Tue, Dec 11th, 2012 
  12 noon -1 pm 

Room Jean-Paul Aubert

Rodolphe 
THIEBAUT

On the use of mechanistic models for HIV clinical trials 

Abstract

Tue, Jan 8th, 2013 
  12 noon -1 pm 

Room Jean-Paul Aubert

Denis MESTIVIER

Modélisation des systèmes biologiques

Abstract

Tue, Feb 5th, 2013
  12 noon -1 pm 

Room Jean-Paul Aubert

Michael HOEHLE

Challenges for statistical modelling during the STEC/HUS outbreak in Germany, 2011 

 Abstract 

Tue, Mar 5th, 2013
  12 noon -1 pm

Room Jean-Paul Aubert  

Steven GOODREAU

HIV Transmission among Men who have Sex with Men (MSM) in the United States and Peru: Insights from Dynamic Demographic Network Models

 Abstract

Tue, Apr 9th, 2013
  12 noon -1 pm

Room Jean-Paul Aubert 

Mercedes PASCUAL

Climate forcing and the population dynamics of infectious diseases in changing human landscapes 

 Abstract

Tue, May 14th, 2013
  12 noon -1 pm 

Room Jean-Paul Aubert 

Chris BAUCH

Vaccine scares and the interplay between disease dynamics and strategic individual vaccinating choices  

 Abstract

Tue, Jun 11th, 2013
  12 noon -1 pm 

Room Jean-Paul Aubert 
  
Updated on 15/05/2014

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