Trypanosome Cell Biology

PHILIPPE BASTIN Lab

 

 

 

Our lab is studying the role and functioning of the trypanosome flagellum, with perspectives in the field of both parasitology and genetic diseases.

 

Indeed, trypanosomes are significant parasites of man and cattle in central Africa and there are currently no efficient vaccines against them. Moreover, trypanosomes are also an excellent model to study human genetic diseases due to defects in cilia and flagella.

 

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Our lab is a Pasteur full research unit and is affiliated to the Department of Parasites and Insect Vectors  and the Department of Cell Biology and Infection. We also belong to a larger INSERM unit (U1201, headed by Artur Scherf) that involves two other teams working on Plasmodium and on Leishmania.

 

Our lab is member of the LabEx IBEID coordinated by Pascale Cossart and Philippe Sansonetti.

 

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"Freedom of speech is essential for scientists"
"La liberté d'expression est essentielle pour les scientifiques"

News

12-05-2015 Cécile is awarded a FRM fellowship to complete her thesis. This will allow to finish her two exciting projects on the role of IFT in mature flagella and on the positioning of IFT trains along axonemal microtubules.

 

01-04-15 Arrival of Estafania Calvo-Alvarez who will work as post-doctoral fellow under Brice's guidance to investigate interactions  between trypanosomes and their environment in vivo.

 

31-03-15 A report summarising the main highlights of the Cilia 2014 meeting has been published in Cilia and is now available at: http://www.ciliajournal.com/content/4/1/5

 

19-03-15 Our review describing approaches to study intraflagellar transport in trypanosomes has just been published in Methods in Cell Biology

 

26-02-15 The video describing sleeping sickness is now available with English subtitles.

 

02-02-15  Eugénie, BSc student, joins our lab for four months. 

 

08-01-2015 Brice and Philippe published a "spotlight" on the possible significance of social motility in trypanosomes

 

 

 

All news

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We and 3 other European groups have organised the 2nd European Cilia meeting in Paris.

The meeting was an impressive success with more than 400 delegates coming from 27 countries. Julien and Cécile gave oral presentations and Eloïse presented a poster.

The next meeting will take place in Amsterdam from 4th to 7th October 2016. 

logogdr.jpgWe are coordinators of the French network GDR CILS that groups 30 teams throughout France working on cilia and flagella in diverse species. 

 

The next meeting will take place in Strasbourg from 12th to 14th October 2015

Next department seminars

25th June 2015

Dr Bruce RUSSELL

National University of Singapore

Zoonotic malaria parasites becoming human

 

9th july 2015

Dr Kiaran Kirk

College of Medicine, Biology & Environment

The Australian National University, Canberra - Australie

Targeting ion transport in the malaria parasite with new-generation antimalarials

 

Click here for more details

 

How to find us

campus1.jpgInstitut Pasteur
25 rue du Docteur Roux
75724 Paris cedex 15
France

tel. +33 1 45 68 86 27
fax. +33 1 40 61 38 25

The lab is located on the first floor of the Nicolle building, n°65 on the Map of Institut Pasteur


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