Biology of Gram positive Pathogens


Patrick TRIEU-CUOT Lab


Low G+C% Gram positive bacteria are constituted by closely related but phylogenetically, physiologically, and genetically distinct genera (bacilli, clostridia, listeria, staphylococci, streptcocci, and enterococci) which share a common ecology, however, as human parasites.






They are considered as leading pathogens causing high morbidity and mortality in humans. In particular, it is estimated that Gram positive cocci (enterococci, streptococci, and staphylococci) produce at least a third of all human bacterial infections, including strep throat (Streptococcus pyogenes), meningitis and pneumonia (Streptococcus pneumoniae and Streptocccus agalactiae), otitis media (S. pneumoniae), food poisoning (Staphylococcus aureus), various skin diseases and severe types of septic shock (S. aureus and S. pyogenes).


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