Azuara, V., Lembezat, M.-P. & Pereira, P.
The homogeneity of the TCRd repertoire expressed by the Thy-1dull gd T cell population is due to cellular selection.
Eur. J. Immunol. 28 : 3456-3467





Godin, I., Garcia-Porrero, J. A., Dieterlen-Lièvre, F. & Cumano, A.
Stem Cell Emergence and Hemopoietic Activity are Incompatible in Mouse Intraembryonic Sites.
J. Exp. Med. 190 : 43-52

Gerber, D., Azuara, V., Levraud, J.-P., Huang, S.Y., Lembezat, M.-P. & Pereira, P.
IL-4-producing gd T cells that express a very restricted TCR repertoire are preferentially localized in liver and spleen.
J. Immunol. 163 : 3076-3082






Barreto, V. & Cumano, A.
Frequency and characterization of phenotypic Ig heavy-chain allelically included IgM-expressing B cells in mice.
J. Immunol. 164: 893-899

Annacker, O., Burlen-Defranoux, O., Pimenta-Araujo, R., Cumano, A. & Bandeira, A.
Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment.
J. Immunol. 164: 3573-3580

Cumano, A., Dieterlen-Lièvre, F. & Godin, I.
The splanchnopleura/AGM region is the prime site for the generation of multipotent hemopoietic precursors, in the mouse embryo.
Vaccine 18: 1621-1623

Azuara, V. & Pereira, P.
Genetic mapping of two murine loci that influences the development of IL-4-producing Thy-1dull gd thymocytes.
J. Immunol. 165 : 42-48

Pereira, P., Hermitte, V., Lembezat, M.-P., Boucontet, L., Azuara, V. & Grigoriadou, K.
Developmentally regulated and lineage-specific rearrangement of T cell receptor Va/d gene segments.
Eur. J. Immunol. 30 : 1988-1997

Douagi, I., André, I., Ferraz, C. & Cumano, A.
Characterization of T-cell precursor activity in the murine fetal thymus : evidence for an input of T cell precursors between days 12 and 14 of gestation.
Eur. J. Immunol. 30 : 2201-2210

Brou, C., Logeat, F., Gupta, N., Bessia, C., LeBail, O., Doedens, J.R., Cumano, A., Roux, P., Black, R.A. & Israel, A.
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.
Mol. Cell. 5 : 207-216

Bousso, P., Wahn, V., Douagi, I., Horneff, G., Pannetier, C., Le Deist, F., Zepp, F., Niehues, T., Kourilsky, P., Fisher, A. & de Saint Basile, G.
Diversity, functionality and stability of the T cell repertoire derived in vivo from a single human T cell precursor.
P.N.A.S. 97 : 274-278

Apostolou, I., Cumano, A., Gachelin, G. & Kourilsky, P.
Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCRab repertoires and differential distribution in lymphoid tissues.
J. Immunol. 165 : 2481-2490

Esposito, G., Godin, I., Klein, U., Yaspo, M.-L., Cumano, A. & Rajewsky, K.
Disruption of the Rev31-encoded catalytic subunit of polymerase z in mice results in early embryonic lethality.
Curr. Biol. 10 : 1221-1224






Azuara, V., Grigoriadou, K., Lembezat, M.-P., Nagler-Anderson, C. & Pereira, P.
Strain-specific TCR repertoire selection of IL-4-producing Thy-1dull gd thymocytes.
Eur. J. Immunol. 31 : 205-214

Annacker, O., Pimenta-Araujo, R., Burlen-Defranoux, O., Barbosa, T.C., Cumano, A. & Bandeira, A.
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10.
J. Immunol. 166 : 3008-3018

Cumano, A. & Godin, I.
Pluripotent hematopoietic stem cell development during embryogenesis.
Curr. Opin. Immunol. 13 : 166-171

Barreto, V., Meo, T. & Cumano, A.
Mice triallelic for the Ig heavy chain locus : implications for VHDJH recombination.
J. Immunol. 166 : 5638-5645

Bensinger, S.J., Bandeira, A., Jordan, M.S., Caton, A.J. & Laufer, T.M.
Major histocompatibility complex Class II-positive cortical epithelium mediates the selection of CD4+25+ immunoregulatory T cells.
J. Exp. Med. 194 : 427-438

Rosmaraki, E. E., Douagi, I., Roth, C., Colucci, F., Cumano, A. & Di Santo, J. P.
Identification of committed NK cell progenitors in adult murine bone marrow.
Eur. J. Immunol. 31:1900-1909

Vigário, M.A., Belnoue, E., Cumano, A., Marussig, M., Miltgen, F., Landau, I., Mazier, D., Gresser, I. & Rénia, L.
Inhibition of Plasmodium yoelii blood-stage malaria by interferon a through the inhibition of the production of its target cell, the reticulocyte.
Blood 97: 3966-3971

Cumano, A., Ferraz, C. J., Klaine, M., Di Santo, J. P. & Godin, I.
Intraembryonic, but not yolk sac-derived hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution.
Immunity 15 : 477-485

Pimenta-Araujo, R., Mascarell, L., Huesca, M., Cumano, A. & Bandeira, A.
Embryonic thymic epithelium naturally devoid of APCs is acutely rejected in the absence of indirect recognition.
J. Immunol. 167 : 5034-5041

Carvalho, T.L., Mota-Santos, T., Cumano, A., Demengeot, J. & Vieira, P.
Arrested B lymphopoiesis and persistence of activated B cells in adult Interleukine 7-/- mice.
J. Exp. Med. 194 : 1141-1150

Annacker, O., Pimenta-Araujo, R., Burlen-Defranoux, O. & Bandeira, A.
On the ontogeny and physiology of regulatory T cells.
Immunol. Rev.182 : 5-17






Douagi, I., Colucci, F., Di Santo, J. P. & Cumano, A.
Identification of the earliest pre-thymic bipotent T /NK progenitor in murine fetal liver.
Blood 99 : 463-471

Pimenta-Araujo, R., Mascarell, L., Huesca, M., Cumano, A. & Bandeira, A.
Deoxyguanosine blocks allograft rejection of thymic epithelium but not lymphocyte infiltration and recognition.
Eur. J. Immunol. 32 : 77-86

Godin, I. & Cumano, A.
The hare and the tortoise : embryonic hematopoietic contest.
Nature Immunol. Rev. 2 : 593-604

Grigoriadou, K., Boucontet, L. & Pereira, P.
T cell receptor-g allele-specific selection of Vg1/Vd4 cells in the intestinal epithelium.
J. Immunol. 169 : 3736-3743

Douagi, I., Vieira, P. & Cumano, A.
Lymphocyte commitment during embryonic development, in the mouse.
Sem. in Immunol. 14 : 361-369







Baron, V., Bouneaud, C., Cumano A., Lim, A., Petteri Arstila, T., Kourilsky, P., Ferradini, L. & Pannetier, C.
The repertoires of circulating human CD8+ central and effector memory T cell subsets are largely distinct.
Immunity 18 : 1-20

O’Garra, A. & Vieira, P.
Twenty-first century Foxp3.
Nature Immunol. 4 : 304-306

Bandeira, A. & Faro, J.
Quantitative constraints on the scope of negative selection : robustness and weakness.
Trends in Immunol. 24 : 172-173

Pereira, J.P., Girard, R., Chaby, R., Cumano, A. & Vieira, P.
Monoallelic expression of the murine gene encoding toll-like receptor 4.
Nature Immunol. 4 : 464-470

Voßhenrich, C.A.J., Cumano, A., Müller, W., Di Santo, J.P. & Vieira, P.
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development.
Nature Immunol. 4 :773-779

Grigoriadou, K., Boucontet, L. & Pereira, P.
Most IL-4-producing gd thymocytes of adult mice originate from fetal precursors.
J. Immunol. 171 : 2413-2420

Nishikawa, S.-I., Honda, K., Vieira, P. & Yoshida, H.
Organogenesis of peripheral lymphoid organs.
Immunol. Rev. 195 : 72-80

Vitry, S., Bertrand, J.Y., Cumano, A.& Dubois-Dalcq M.
Primordial hematopoietic stem cells generate microglia but not myelin-forming cells in a neural environment.
J. Neuroscience 23 : 10724-10731

Goudeau, B., Huetz, F., Samson, S., Di Santo, J.P., Cumano, A., Beg, A., Israël, A. & Mémet, S.
IkBa/IkBe deficiency reveals that a critical NF-kB dosage is required for lymphocyte survival.
P.N.A.S. 100 : 15800-15805







Faro, J., Velasco, S., Gonzalez-Fernandez, A. & Bandeira, A.
The impact of thymic antigen diversity on the size of the selected T cell repertoire.
J. Immunol. 172 : 2247-2255

Vieira, P. & Cumano, A.
Differentiation of B lymphocytes rom hematopoietic stem cells.
In Methods in Molecular Biology. Eds Gu H. and Rajewsky K., Humana Press. 271 : 67-76

Vosshenrich, C.A.J., Cumano, A., Müller, W., Di Santo, J.P. & Vieira, P.
Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment.
P.N.A.S 101 : 11070-11075

O’Garra, A. & Vieira, P.
Regulatory T cells and mechanisms of immune system control.
Nature Med. 10 : 801-805

Gerber, D., Boucontet, L. & Pereira, P.
Early expression of a functional TCRb chain inhibits TCRg gene rearrangements without altering the frequency of TCRgd lineage cells.
J. Immunol. 173 : 2516-2523

Pereira, P. & Boucontet, L.
Rates of recombination and chain pair biases greatly influence the primary gd TCR repertoire in the thymus of adult mice.
J. Immunol. 173 : 3261-3270

Dujardin, H.C., Burlen-Defranoux, O., Boucontet, L., Vieira, P., Cumano, A. & Bandeira, A.
Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells.
P.N.A.S. 101 : 14473-14478

O’Garra, A., Vieira, P.L., Vieira, P. & Goldfeld, A.E.
IL-10-producing and naturally occurring CD4+ Tregs : limiting collateral damage.
J. Clin. Invest. 114 : 1372-1378

Bertrand, J.Y., Giroux, S., Cumano, A. & Godin, I.
Hematopoietic stem cell development during mouse embryogenesis.
Methods Mol. Med. 105 : 273-288

Six, E.M., Ndiaye, D., Sauer, G., Laabi, Y., Athman, R., Cumano, A., Brou, C., Israel, A. & Logeat, F.
The Notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration.
J. Biol. Chem. 279 : 55818-55826







Bertrand, J.Y., Giroux, S., Golub, R., Klaine, M., Jalil, A., Boucontet, L., Godin, I. & Cumano, A.
Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin.
P.N.A.S. 102 : 134-139

De La Coste, A., Six, E., Fazilleau, N., Mascarell, L., Legrand, N., Mailhe, M.-P., Cumano, A., Laabi, Y. & Freitas, A.A.
In vivo and in absence of a thymus the enforced expression of the Notch ligands Delta-1 or Delta-4 promotes T cell development with specific unique effects.
J. Immunol. 174 : 2730-2737

Boucontet, L., Sepulveda, N., Carneiro J. & Pereira, P.
Mechanisms controlling termination of V-J recombination at the TCRg locus : implications for allelic and isotypic exclusion of TCRg chains.
J. Immunol. 174 : 3912-3919

Dias, S., Silva Jr, H., Cumano, A. & Vieira, P.
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors.
J. Exp. Med. 201 : 971-979

Sepulveda, N., Boucontet, L., Pereira, P. & Carneiro, J.
Stochastic modeling of T cell receptor g gene rearrangement.
J. Theor. Biol. 234 : 153-165

Shin, S., El-Diwany, R., Schaffert, S., Adams, E.J., Garcia, K.C., Pereira, P. & Chien, Y.-H.
Antigen recognition determinants of gd T cell receptors.
Science 308 : 252-255

Godin, I. & Cumano, A.
Of birds and mice : hematopoietic stem cell development.
Int. J. Dev. Biol. 49 : 251-257

Meignin, V., Peffault de Latour, R., Zuber, J., Régnault, A., Mounier, N., Lemaître, F., Dastot, H., Itzykson, R., Devergie, A., Cumano, A., Gluckman, E., Janin, A., Bandeira, A. & Socié, G.
Numbers of Foxp3-expressing CD4+CD25high T cells do not correlate with the establishment of long-term tolerance after allogeneic stem cell transplantation.
Exp. Hemato. 33 : 894-900

Montarras, D., Morgan, J., Collins, C., Relaix, F., Zaffran, S., Cumano, A., Partridge, T. & Buckingham, M.
Direct isolation of satellite cells for skeletal muscle regeneration.
Science 309 : 2064-2067

Bertrand, J.Y., Jalil A., Klaine, M., Jung, S., Cumano, A. & Godin, I.
Three pathways to mature macrophages in the early mouse yolk sac.
Blood 106 : 3004-3011







Relaix, F., Montarras, D., Zaffran, S., Gayraud-Morel, B. Rocancourt, D., Tajbakhsh, S., Mansouri, A., Cumano, A. & Buckingham, M.
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.
J. Cell Biol. 172 : 91-102

Fogg, D.K., Sibon, C., Miled, C., Jung, S., Aucouturier, P., Littman, D.R., Cumano, A. & Geissmann, F.
A clonogenic bone marrow progenitor specific for macrophages and dendritic cells.
Science 311 : 83-87

Rybner-Barnier, C., Jacquemot, C., Cuche, C., Doré, G., Majlessi, L., Gabellec, M-M., Moris, A., Schwartz, O., Di Santo, J., Cumano, A., Leclerc, C. & Lazarini, F.
Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells.
J. Virol. 80 : 4656-4663

Peffault de Latour, R., Dujardin, H.C., Mishellany, F., Burlen-Defranoux, O., Zuber, J., Marques, R., Di Santo, J., Cumano, A., Vieira, P. & Bandeira, A.
Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7.
Blood 108 : 2300-2306

Bertrand, J.Y., Desanti, G.E., Lo-Man, R., Leclerc, C., Cumano, A. & Golub, R.
Fetal spleen stroma drives macrophage commitment.
Development 133 : 3619-3628

Boonstra, A., Rajsbaum, R., Holman, M., Marques, R., Asselin-Paturel, C., Pereira, J.P., Bates, E.E.M., Akira, S., Vieira, P., Liu, Y.-J., Trinchieri, G. & O’Garra, A.
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.
J. Immunol., 177 : 7551-7558

Vosshenrich, C.A., Garcia-Ojeda, M.E., Samson-Villegier, S.I., Pasqualetto, V., Enault, L., Richard-Le Goff, O., Corcuff, E., Guy-Grand, D., Rocha, B., Cumano, A., Rogge, L., Ezine, S. & Di Santo, J.P.
A thymic patwhay of mouse natural killer cell development characterized by expression of GATA-3 and CD127.
Nature Immunol. 7 : 1217-1224







Cumano, A. & Godin, I.
Ontogeny of the hematopoietic system.
Annu. Rev. Immunol. 25 : 745-785

O’Garra, A. & Vieira, P.
TH1 cells control themselves by producing interleukin-10.
Nature Rev. Immunol. 7 : 725-428

Zuber, J., Viguier, M., Lemaitre, F., Senée, V., Patey, N., Elain, G., Geissmann, F., Fakhouri, F., Ferradini, L., Julier, C. & Bandeira, A.
Severe Foxp3+ and naïve T lymphopenia in a non-IPEX form of autoimmune enteropathy combined with an immunodeficiency.
Gastroenterology 132 : 1694-1704

Vigario, A.M., Gorgette, O., Dujardin, H.C., Cruz, T., Cazenave, P.-A., Six, A., Bandeira, A. & Pied, S.
Regulatory CD4+CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria.
Int. J. Parasitology 37 : 963-973

Auffray, C., Fogg, D., Garfa, M., Elain, G., Join-Lambert, O., Kayal, S., Sarnacki, S., Cumano, A., Lauvau, G. & Geissmann, F.
Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior.
Science 317 : 666-670

Vieira, P. & O’Garra, A.
Regula’ten’ the gut.
Nature Immunol. 8 : 905-907

Vieria, P., Vosshenrich, C., Cumano, A., Müller, W., Di Santo, J.P., Pereira de Sousa, A. & Lalanne, A.I.
Reply to « TSLP-mediated fetal B lymphopoiesis ? » (correspondence).
Nature Immunol. 8 : 897-898

Thiriot, A., Drapier, A.-M., Vieira, P., Fitting, C., Cavaillon, J.-M., Cazenave, P.-A. & Rueff-Juy, D.
The Bw cells, a novel B cell population conserved in the whole genus Mus.
J. Immunol. 179 : 6568-6578

Desanti, G., Bertrand, J.Y. & Golub, R.
Fetal spleen development, the ride toward multiple functions.
Functional Dev. & Embryology 1 : 78-90







Delaunay, D., Heydon, K., Cumano, A., Schwab, M.H., Thomas, J.-L., Suter, U., Nave, K.-A., Zalc, B. & Spassky, N.
Early neuronal and glial fate restriction of embryonic neural stem cells.
J. Neuroscience 28 : 2551-2562 (2008)

Kieusseian, A. & Cumano, A.
Are hematopoietic stem cells generated in the placenta ?
Cell Stem Cell 2 : 197-198

Desanti, G.E., Cumano, A. & Golub, R.
Identification of CD4int progenitors in mouse fetal spleen, a source of resident lymphoid cells.
J. Leukocyte Biol. 83 : 1145-1154

Vondenhoff, M.F.R., Desanti, G.E., Cupedo, T., Bertrand, J.Y., Cumano, A., Kraal, G., Mebius, R.E. & Golub, R.
Separation of splenic red and white pulp occurs before birth in a LTab-independent manner.
J. Leukocyte Biol. 84 : 152-161

Chéret, C., Gervais, A., Lelli, A., Colin, C., Amar, .L, Ravassard, P., Mallet, J., Cumano, A., Krause, K.H., Mallat, M.
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.
J. Neuroscience 28 : 12039-12051.

Mesquita, A.R., Correia-Neves, M., Roqu,e S., Gil Castro, A., Vieira, P., Pedrosa, J., Almeida Palha, J. & Sousa, N.
IL-10 modulates depressive-like behavior.
J. Psychiatric Res, 43: 89-97







Boucontet, L., Grana, M., Alzari, P.M. & Pereira, P.
Mechanisms determining cell membrane expression of different gd TCR chain pairings.
Eur. J. Immunol. 39 : 1937-1946

Alves, N.L., Richard-Le Goff, O., Huntington, N.D., Sousa, A.P., Ribeiro, V.S., Bordack, A., Vives, F.L., Peduto, L., Chidgey, A., Cumano, A., Boyd, R., Eberl, G. & Di Santo, J.P.
Characterization of the thymic IL-7 niche in vivo.
P.N.A.S. 106  1512-1517.

Auffray, C., Fog,g D.K., Narni-Mancinelli, E., Senechal, B., Trouillet, C., Saederup, N., Leemput, J., Bigot, K., Campisi, L., Abitbol, M., Molina, T., Charo, I., Hume, D.A., Cumano, A., Lauvau, G. & Geissmann, F.
CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation.
J. Exp. Med. 206 : 595-606

Peduto, L., Dulauroy, S., Lochner, M., Späth, G..F, Morales, M.A., Cumano, A. & Eberl, G.
Inflammation recapitulates the ontogeny of lymphoid stromal cells.
J. Immunol. 182  5789-5799

Huntington, N.D., Labi, V., Cumano, A., Vieira, P., Strasser, A., Villunger, A., Di Santo, J.P. & Alve,s N.L.
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.
Int. Immunol. 21  715-725.

Crist, C.G., Montarras, D., Pallafacchina, G., Rocancourt, D., Cumano, A., Conway, S.J. & Buckingham, M.
Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.
P.N.A.S. 106 : 13383-13387

Kreslavsky, T., Savage, A., Hobbs, R., Gounari, F., Bronson, R., Pereira, P., Pandolfi, P.P., Bendelac,  A. &  von Boehmer, H.
TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gd T cells with restricted TCR diversity.
P.N.A.S. 106 : 12453-12458

Jory, A., Le Roux, I., Gayraud-Morel, B., Rocheteau, P., Cohen-Tannoudji, M., Cumano, A. & Tajbakhsh, S.
Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite.
Stem Cells  27 : 2769-2780

Lagha, M., Brunelli, S., Messina, G., Cumano, A., Kume, T., Relaix, F. & Buckingham, M.E.
Pax3 :Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors.
Dev. Cell 17 : 892-899








Alonzo, E.S., Gottschalk, R.A., Das, J., Egawa, T., Hobbs, R.M., Pandolfi, P.P., Pereira, P., Nichols, K.E., Koretzky, G.A., Jordan, M.S. & Sant’Angelo, D.B.
Development of promyelocytic zinc finger and ThPOK-expressing innate gd T cells is controlled by strength of TCR signaling and Id3.
J. Immunol. 184 : 1268-1279

Satoh-Takayama, N., Lesjean-Pottier, S., Vieira, P., Sawa, S., Eberl, G., Voßhenrich, C.A.J. & Di Santo, J.P.
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors.
J. Exp. Med. 207 : 273-280

Verykokakis, M., Boos, M.D., Bendelac, A., Adams, E.J., Pereira, P. & Kee, B.L.
Inhibitor of DNA binding 3 limits development of murine slam-associated adaptor protein-dependent « innate » gd T cells.
PLoS ONE 5 : e9303

Montaudouin, C., Boucontet, L., Mailhe-Lembezat, M.-P., Mariotti-Ferrandiz, M.-E., Louise, A., Six, A., Freitas, A.A. & Garcia, S.
Endogenous TCR recombination in TCR Tg single Rag-deficient mice uncovered by robust in vivo T cell activation and selection.
PLoS ONE : e10238

Lalanne, A.I., Moraga, I., Hao, Y., Pereira, J.P., Alves, N.L., Huntington, N.D., Freitas, A.A., Cumano, A. & Vieira, P.
CpG inhibits Pro-B cell expansion through a cathepsin B-dependent mechanism.
J. Immunol. 184 : 5678-5685

Lescale, C., Dias, S., Maës, J., Cumano, A., Szabo, P., Charron, D., Weksler, M.E., Dosquet, C., Vieira, P. & Goodhardt, M.
Reduced EBF expression underlies loss of B cell potential of hematopoietic progenitors with age.
Aging Cell 9 : 410-419

Pallafacchina, G., François, S., Regnault, B., Czarny, B., Dive, V., Cumano, A., Montarras, D. & Buckingham, M.
An adult tissue-specific stem cell in its niche : a gene profiling analysis of in vivo quiescent and activated muscle satellite cells.
Stem Cell Res. 4 : 77-91

Mouly, E., Chemin, K., Nguyen, H.V., Chopin, M., Menard, L., Leite-de-Moraes, M., Burlen-Defranoux, O., Bandeira, A. & Bories, J.-C.
Gene targeted inactivation of Ets-1 triggers systemic autoimmunity due to impaired development and function of Foxp3 regulatory T-cells.
J. Exp. Med. 207 : 2113-2125

Ribeiro, V.S.G., Hasan, M., Wilson, A., Boucontet, L., Pereira, P., Lesjean-Pottier, S., Satoh-Takayama, N., Di Santo, J.P. & Vosshenrich, C.A.J.
Cutting edge : thymic NK cells develop independently from T cells precursors.
J. Immunol. 185 : 4993-4997

Lagha, M., Sato, T., Regnault, B., Cumano, A., Zuniga, A., Licht, J., Relaix, F. & Buckingham, M.
Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.
BMC Genomics 11 : 696








Demarque, M.D., Nacerddine, K., Neyret-Kahn, H., Andrieux, A., Danenberg, E., Jouvion, G., Bomme, P., Hamard, G., Romagnolo, B., Terris, B., Cumano, A., Barker, N., Clevers, H. & Dejean, A.
Sumoylation by Ubc9 regulates the stem cell compartment and structure and function of the intestinal epithelium in mice.
Gastroenterology 140 : 286-296

Ma, Y., Aymeric, L., Locher, C., Mattarollo, S.R., Delahaye, N.F., Pereira, P., Boucontet, L., Apetoh, L., Ghringhelli, F., Casares, N., Lasarte, J.J., Matsuzaki, G., Ikuta, K., Ryffel, B., Benlagha, K., Tesniere, A., Ibrahim, N., Déchanet-Merville, J., Chaput, N., Smith, M.J., Kroemer, G. & Zitvogel, L.
Contribution of IL-17-producing γδ T cells to the efficacy of anticancer chemotherapy.
J. Exp. Med. 208 : 491-503

Soulard, V., Amadoudji Zin, M., Fitting, C., Ibitokou, S., Oesterholt, M., Luty, A.J., Perrin, R.X., Massougbodji, A., Deloron, P., Bandeira, A. & Fievet, N.
Placental malaria-associated suppression of parasite-specific immune response in neonates has no major impact on systemic CD4 T cell homeostasis.
Infect. Immun. 79 : 2801-2809

Lopes, M., Goupille, O., Saint Cloment, C., Lallemand, Y., Cumano, A. & Robert, B.
Msx genes define a population of mural cell precursors required for head blood vessel maturation.
Development 138 : 3055-3066

Lagranderie, M., Kluge, C., Kieffer-Biasizzo, H., Abolhassani, M., Nahori, M.-A., Fitting, C., Huerre, M., Bandeira, A., Bercovier, H. & Marcha,l G.
Mycobacterium bovis bacillus Calmette-Guérin killed by extended freeze-drying reduces colitis in mice.
Gastroenterology 141 : 642-652

Possot, C., Schmutz, S., Chea, S., Boucontet, L., Louise, A., Cumano, A. & Golub, R.
Notch signaling is necessary for adult, but not fetal, development of RORγt+ innate lymphoid cells.
Nature Immunol. 12 : 949-959

Goupille, O., Pallafacchina, G., Relaix, F., Conway, S.J., Cumano, A., Robert, B., Montarras, D. & Buckingham, M.
Characterization of Pax3-expressing cells from adult blood vessels.
J. Cell. Sci. 124 : 3980-3988







Pereira, P., Boucontet, L. & Cuman,o A.
Temporal predisposition to αβ and γδ T cell fates in the thymus.
J. Immunol. 188 : 1600-1608

Pereira, P. & Boucontet, L.
Innate NKTγδ and NKTαβ cells exert similar functions and compete for a thymic niche.
Eur. J. Immunol. 42 : 1272-1281

Gayraud-Morel, B., Chrétien, F., Jory, A., Sambasivan, R., Negroni, E., Flamant, P., Soubigou, G., Coppée, J.-Y., Di Santo, J., Cumano, A., Mouly, V. & Tajbakhsh, S.
Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells.
J. Cell Sci. 125 : 1738-1749

Chen, Y., Ci, X., Gorentla, B., Sullivan, S.A., Stone, J.C., Zhang,, W., Pereira P., Lu, J. & Zhong, X.-P.
Differential requirement of RasGRP1 for γδ T cell development and activation.
J. Immunol. 189 : 61-71

Kieusseian, A., Brunet de la Grange, P., Burlen-Defranoux, O., Godin, I. & Cuman,o A.
Immature hematopoietic stem cells undergo maturation in the fetal liver.
Development 139 : 3521-3530

Pereira de Sousa, A., Berthault, C., Granato, A., Dias, S., Ramond, C., Kee, B.L., Cumano, A. & Vieira, P.
Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors.
J. Immunol. 189 : 3822-3830

Rueda, P., Richart, A., Récald,e A., Gasse, P., Vilar, J., Guérin, C., Lortat-Jacob, H., Vieira, P., Baleux, F., Chretien, F., Arenzana-Seisdedos, F. & Silvestre J.-S.
Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions.
Circulation 126 : 1882-1895

Hess, E., Duheron, V., Decossas, M., Lézot, F., Berdal, A., Chea, S., Golub, R., Bosisio, M.R., Bridal, S.L. Choi, Y., Yagita, H. & Mueller, C.G.
RANKL induces organized lymph node growth by stromal cell proliferation.
J. Immunol. 188 : 1245-1254







Garcia-Ojeda, M.E., Klein Wolterink, R.G., Lemaitre, F., Richard-Le Goff, O., Hasan, M., Hendriks, R.W., Cumano, A. & Di Santo, J.P.
GATA-3 promotes T cell specification by repressing B cell potential in pro-T cells.
Blood 121 : 1749-1759

Guy-Grand, D., Vassalli, P., Eberl, G., Pereira, P., Burlen-Defranoux, O., Lemaitre, F., Di Santo, J. P., Freitas, A.A., Cumano, A. & Bandeira, A.
Origin, trafficking, and intraepithelial fate of gut-tropic T-cells.
J. Exp. Med. 210 : 1839-1854

Fevre, C., Almeida, A.S., Taront, S., Pedron, T., Huerre, M., Prevost, M.-C., Kieusseian, A., Cumano, A., Brisse, S., Sansonetti, P.J. & Tournebize, R.
A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
EMBO Mol. Med. 5 : 516-530

Le Bouteiller, M., Souilhol, C., Beck-Cormier, S., Stedman, A., Burlen-Defranoux, O., Vandormael-Pournin, S., Bernex, F., Cumano, A. & Cohen-Tannoudji, M.
Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells.
J. Exp. Med. 210 : 2351-2369

Golub, R. & Cumano, A.
Embryonic hematopoiesis.
Blood Cells Mol. Dis. 51 : 226-231

Pereira, P., Berthault, C., Burlen-Defranoux, O. & Boucontet, L.
Critical role of TCR specificity in the development of Vγ1Vδ6.3+ innate NKTγδ cells.
J. Immunol. 191 : 1716-1723

Carpentier, M., Chappert, P., Kuhn, C., Lalfer, M., Flament, H., Burlen-Defranoux, O., Lantz, O., Bandeira, A., Malissen, B., Davoust, J. & Gross, D.A.
Extrathymic induction of Foxp3? regulatory T cells declines with age in a T-cell intrinsic manner.
Eur J. Immunol. 43 : 2598-604







Ramond, C., Berthault, C., Burlen-Defranoux, O., Pereira de Sousa, A., Guy-Grand, D., Vieira, P., Pereira, P. & Cumano, A.
Two waves of distinct hematopoietic progenitors cells colonize the fetal thymus.
Nature Immunol. 15 : 27-35


Golub, R., Vieira, P. & Cumano, A.

Hematopoiesis during embryonic development

In Stem Cells. From basic research to therapy. Vol 1. Calegari F. & Waskow C. Eds; CRC Press 185-212


Duffy, D., Rouilly, V., Libri, V., Hasan, M., Beitz, B., David, M., Urrutia, A., Bisiaux, A., LaBrie, S., Dubois, A., Boneca, I.G., Delval, C., Thomas, S., Rogge, L., Schmolz, M., Quintana-Murci, L., Albert, M. & Milieu Interium Consortium.

Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli.

Immunity 40 : 436-450


Chrisment, D., Dubus, P., Chambonnier, L., Hocès de la Guardia, A., Sifré, E., Giese, A., Capone, M., Khairallah, C., Costet, P., Rousseau, B., Hubert, C., Burlen-Defranoux, O., Varon, C., Bandeira, A., Mégraud, F. & Lehours, P.

Neonatal thymectomy favors Helicobacter pylori- promoted gastric mucosa-associated lymphoid tissue lymphoma lesions in BALB/c mice.

Am. J. Pathology 184 : 2174- 2184


Pereira Gonçalves, N., Vieira, P. & Saraiva M.J.

Interleukin-1 signaling pathway as a therapeutic target in transthyrein amyloidosis.

Amyloid 21 : 175-184


Valente, M., Nascimento, D.S., Cumano, A. & Pinto-do-O, P.

Sca-1+ cardiac progenitor cells and heart-making : a critical synopsis

Stem Cells Dev 23 : 2263-2273


Saggio, I., Remoli, C., Spica, E., Cersosimo, S., Sacchetti, B., Robey, P.G., Holmbeck, K., Cumano, A., Boyde, A., Bianco, P. & Riminucci, M.

Constitutive expression of GsaR201C in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history.

J. Bone Miner. Res. 29: 2357-2368


Blanco, R., Borroto, A., Schamel, W., Pereira, P. & Alarcon, B.

Conformational changes in the T cell receptor differentially determine T cell subset development in mice.

Science Signaling 7 : ra115


Alves-Pereira, C.F., de Freitas, R., Lopes, T., Gardner, R., Marta, F., Vieira, P. & Barreto V.M.

Independent recruitment of Igh alleles in V(D)J recombination.

Nature Communications : 5623





Boulay, A.-C., Mazeraud, A., Cisternino, S., Saubaméa, B., Mailly, P., Jourdren, L., Blugeon, C., Mignon, V., Smirnova, M., Cavalla, A., Ezan, P., Avé, P., Dingli, R., Loew, D., Vieira, P., Chrétien, F. & Cohen-Salomon, M.
Immune quiescience of the brain is set by astrogrial connexin 43.
J. Neuroscience 35 : 4427-4439


Chen, X., Hasan, M., Libri, V., Urrutia, A., Beitz, B., Rouilly, V., Duffy, D., Patin, E., Chalmond, B., Rogge, L., Quintana-Murci, L., Albert, M.L., Schwikowski, B. & Milieu Interieur Consortium.

Automated flow cytometric analysis across large numbers of samples and cell types.

Clinical Immunol. 157 : 249-260


Remoli, C., Michienzi, S., Sacchetti, B., Di Consiglio, A., Cersosimo, S., Spica, E., Robey, P.G., Holmbeck, K., Cumano, A., Boyde, A., Davis, G., Saggio, I., Riminucci, M. & Bianco, P.

Osteoblast-specific expression of the Fibrous Dysplasia (FD) causing mutation GsaR201C produces a high bone mass phenotype but does not reproduce FD in the mouse.

J. Bone Miner. Res. 30 : 1030-1043


Santos, J.M., Camoes, S.P., Filipe, E., Cipriano, M., Barcia, R.N., Filipe, M., Teixeira, M., Simoes, S., Gaspar, M., Mosqueira, D., Nascimento, D.S., Pinto-do-O, P., Cruz, P., Cruz, H., Castro, M. & Miranda J.P.

Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing.

Stem Cell Res. & Therapy 6:90

Updated on 18/06/2015


Lymphopoiesis Unit
Institut Pasteur
25 Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE

Tel 33 1 45 68 82 55
Secretary 33 1 45 68 85 93
Fax 33 1 45 68 89 21



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