Positions available

Postdoc and PhD students

 

One position for postdoc or PhD student is available in the stroma team of the Lymphoid Tissue Development (LTD) Unit to study the regulation of immune responses by stromal cells, in particular in chronic pathologies such as fibrosis and cancer. We have previously shown that inflammatory lesions need to develop a specialized gp38+ stromal network to organize the recruitment and survival of lymphocytes (Peduto et al., JI 2009). We further identified a subset of gp38+ stromal cell induced by inflammation, co-expressing ADAM12 and PDGFRα, as a major source for scar tissue after acute injury (Dulauroy et al., Nature Medicine 2012). We now aim at deciphering the underlying mechanism(s), and how dysregulation of a proper stromal balance contribute to the pathogenesis of chronic diseases. Please send applications to: lucie.peduto@pasteur.fr.

 

The LTD Unit is recruiting one postdoctoral fellow to study the regulation of the microbiota, metabolism and adaptive immune system by innate lymphoid cells (ILCs). We have shown how ILCs develop from common lymphoid progenitors, and fate-mapped the ILC3 lineage (Sawa, Science 2010, Cherrier, JEM 2012). We have also shown how microbiota regulates the activity of ILCs (Sawa, Nat Immunol, 2011) and the role of type 3 immunity in maintaining intestinal homeostasis (Lochner, JEM 2011). We now wish to understand the role of ILCs in the regulation of microbiota, metabolism and adaptive immunity using a series of newly developed mouse models. Please send applications to: gerard.eberl@pasteur.fr.

 

The positions are open for 2015. Applicants should have a strong background in cellular immunology, cell biology or physiology, be highly motivated to do research in these competitive and exciting areas, and show an innate ability to work as a team. Experience in transcriptional analysis, multi-parameter flow cytometry and/or mouse models are highly desirable. The LTD Unit enjoys numerous collaborations with researchers on campus and beyond that are necessary to advance in the multi-disciplinary fields of mucosal immunology and inflammation. The Pasteur campus offers top expertise in microbiology and immunology, as well as cutting-edge technical platforms, all of which are essential to progress at these scientific frontiers.

Updated on 11/11/2014

Contacts

Gérard EBERL

+33 (0)1 44 38 94 46

geberl@pasteur.fr
 

Lucie PEDUTO

+33 (0)1 44 38 94 27

pedutol@pasteur.fr

Positions available

Two postdoctoral or PhD positions are available.

 

One position is to study the regulation of immune responses by stromal cells, in particular in chronic pathologies such as fibrosis and cancer.

 

The second position is to study the regulation of the microbiota, metabolism and adaptive immune system by innate lymphoid cells (ILCs).

 

The positions are open for 2015. Applicants should have a strong background in cellular immunology, cell biology or physiology, be highly motivated to do research in this competitive and exciting area, and show an innate ability to work as a team.

 

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