The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
CANCER FROM WITHIN: immune cells reveal insights into mechanisms of DNA recombination and tumorigenesis
Lymphocytes are unique cell types of our adaptive immune system that require multiple rounds of cell divisions during their development and, most strikingly, multiple rounds of gene rearrangements during the formation of their antigen receptors. This stepwise process puts their genome integrity in danger. Quoting the hemato-oncologist Louis Staudt "normal lymphocyte differentiation is, in some sense, a disaster waiting to happen". Indeed, lymphoma and leukemia are amongst the most common human neoplastic disorders.
Our major goal is to understand the mechanisms by which a lymphoid cell maintains the integrity of its DNA and prevents genomic instability and transformation. More precisely, we study the DNA recombination processes that are part of B- and T-cell development and the mechanisms and pathways that lead to lymphoid cancers.
Lab members (left to right): Tyama El Chaar, Joy Bianchi, Nicole Clarke, Christophe Clouin, Valentine Murigneux, Chloé Lescale, Ludovic Deriano, Marie Bedora-Faure.