Human Evolutionary Genetics

Our research is focused on understanding how natural selection, human demography and lifestyle have shaped the patterns of diversity of the human genome in different populations worldwide.

In particular, we are interested in exploring how infectious diseases have exerted selective pressures on human genes involved in immunity and host defence in order to unmask immunological mechanisms that have been critical for our past and present survival. To this end, our laboratory combines molecular and population genetics approaches with computational modelling, often working closely to theoretical population geneticists, immunologists, epidemiological geneticists as well as anthropologists.

 

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Our laboratory is located in the Department of Genomes and Genetics at the Institut Pasteur in Paris. The lab is associated to the CNRS (URA3012) and receives funding from the Institut Pasteur, CNRS, Fondation pour la Recherche Médicale, Agence Nationale de la Recherche and National Geographic.

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