Epigenetic Regulation


Christian Muchardt


Over the recent years, several fascinating discoveries have revealed an implication of RNA molecules in the regulation of chromatin condensation and transcription.




A connection between RNAs and factors regulating transcription is not surprising as RNA is by definition an integer component of the transcription machinery.

However, our knowledge of this connection is still very restricted and there is a clear need of a more comprehensive characterization of the crosstalk between the transcription machinery and the RNAs that this machinery produces.

The objective of our group is to investigate this crosstalk, defining the proteins, the RNAs and the mechanisms involved, in an attempt to achieve an overview on its impact on transcriptional regulation in a broad sense.


Epigenetic Regulation (URA CNRS 2578)


Mail address :
Monod Building
Institut Pasteur
25, rue du Docteur Roux
75724 PARIS CEDEX 15

Phone : 33 1 45 68 85 25
Fax : 33 1 45 68 89 76


Location : 4th floor of the Monod building (building 66), rooms 01 and 07



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