The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
Citizenship French Professional address :
Bacteria-cell interactions Unit – INSERM U604 – INRA USC2020
Department of Cell biology and Infection
25 rue du Docteur Roux -75724 PARIS Cedex 15-France.
Present position and status: Staff scientist, Engineer
UNIVERSITARY EDUCATION 1988 Ph.D. in Molecular Virology, University Louis Pasteur, Strasbourg I, France. 1984 Master in Cellular and Molecular Biology (DEA), University Louis Pasteur, Strasbourg I, France. 1983 Degree in Biochemistry, University Louis Pasteur, Strasbourg I, France.
RESEARCH EXPERIENCE 2004-Present Research Engineer, Unité des Interactions Bactéries-Cellules, Institut Pasteur, Paris, France. In charge of microscopes. Study on new functions of listeria proteins. 1995-2004 Research Engineer, Unité de Neurovirologie et Régénération du Système Nerveux, Institut Pasteur, Paris, France. "Differential signalization of the CXCR4 receptor by the alpha chemokine stromal cell-derived factor SDF-1 in the central nervous system of the rat and migration stimulization of multipotent neural precursors of the striatum". 1993-1994 Research Engineer, Unité de virologie médicale et vaccins viraux, Institut Pasteur, Paris, France. "In vivo persistence of Hepatitis Virus A". 1990-1993 Post-doctoral Fellow, Oncologie virale, Départment des Rétrovirus, Institut Pasteur, Paris, France. "Localization and identification of the adhesin gene of Mycoplasma pirum isolated from AIDS patients". 1988-1990 Post-doctoral Fellow, Laboratoire des sondes froides, Department of Immunology, Pasteur Institute, Paris. "Biotinylated oligonucleotide probes for the detection and the characterization of TEM-type extended broad spectrum ß-lactamases in Enterobacteriaceae".
SELECTED PUBLICATION LIST
1. Tetraspanin CD81 is required for Listeria monocytogenes invasion.
Tham TN, Gouin E, Rubinstein E, Boucheix C, Cossart P, Pizarro-Cerda J.
Infect Immun. 2010 Jan;78(1):204-9. Epub 2009 Nov 9.
2. Human BAHD1 promotes heterochromatic gene silencing.
Bierne H, Tham TN, Batsche E, Dumay A, Leguillou M, Kernéis-Golsteyn S, Regnault B, Seeler JS, Muchardt C, Feunteun J, Cossart P.
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13826-31. Epub 2009 Aug 3.
3. Septins regulate bacterial entry into host cells.
Mostowy S, Nam Tham T, Danckaert A, Guadagnini S, Boisson-Dupuis S, Pizarro-Cerdá J, Cossart P.
PLoS One. 2009;4(1):e4196. Epub 2009 Jan 15.
4. Histone modifications induced by a family of bacterial toxins.
Hamon MA, Batsché E, Régnault B, Tham TN, Seveau S, Muchardt C, Cossart P.
Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13467-72. Epub 2007 Aug 3. Erratum in: Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17555.
5. A FRET analysis to unravel the role of cholesterol in Rac1 and PI 3-kinase activation in the InlB/Met signalling pathway.
Seveau S, Tham TN, Payrastre B, Hoppe AD, Swanson JA, Cossart P.
Cell Microbiol. 2007 Mar;9(3):790-803. Epub 2006 Nov 28.
Updated on 12/05/2014
Unité Interactions Bactéries-Cellules
INSERM U604 INRA USC2020
25, Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE
Phone: + 33 (1) 45 68 88 41
Secretary: + 33 (1) 40 61 30 32
Fax: + 33 (1) 45 68 87 06
Our laboratory is located on the ground floor at the 53C entrance of the Roux Building (25, rue du Docteur Roux)
The metro stations Pasteur (line 6) and Volontaires (line 12) are within a 5 min walking distance from the Pasteur Institute.
The bus stop Pasteur (bus 95, towards Porte de Vanves) is located next to the Pasteur Institute main entrance.