Curriculum vitae To Nam Tham


Citizenship                                French
Professional address :
Bacteria-cell interactions Unit – INSERM U604 – INRA USC2020
Department of Cell biology and Infection
25 rue du Docteur Roux -75724 PARIS Cedex 15-France.
E-mail: tonamtham.png

Present position and status:        Staff scientist, Engineer


1988     Ph.D. in Molecular Virology, University Louis Pasteur, Strasbourg I, France.
1984     Master in Cellular and Molecular Biology (DEA), University Louis Pasteur, Strasbourg I, France.
1983     Degree in Biochemistry, University Louis Pasteur, Strasbourg I, France.


2004-Present     Research Engineer, Unité des Interactions Bactéries-Cellules, Institut Pasteur, Paris, France. In charge of microscopes. Study on new functions of listeria proteins.
1995-2004          Research Engineer, Unité de Neurovirologie et Régénération du Système Nerveux, Institut Pasteur, Paris, France. "Differential signalization of the CXCR4 receptor by the alpha chemokine stromal cell-derived factor SDF-1 in the central nervous system of the rat and migration stimulization of multipotent neural precursors of the striatum".
1993-1994          Research Engineer, Unité de virologie médicale et vaccins viraux, Institut Pasteur, Paris, France. "In vivo persistence of Hepatitis Virus A".
1990-1993          Post-doctoral Fellow, Oncologie virale, Départment des Rétrovirus, Institut Pasteur, Paris, France. "Localization and identification of the adhesin gene of Mycoplasma pirum isolated from AIDS patients".
1988-1990          Post-doctoral Fellow, Laboratoire des sondes froides, Department of Immunology, Pasteur Institute, Paris. "Biotinylated oligonucleotide probes for the detection and the characterization of TEM-type extended broad spectrum ß-lactamases in Enterobacteriaceae".


1. Tetraspanin CD81 is required for Listeria monocytogenes invasion.
Tham TN, Gouin E, Rubinstein E, Boucheix C, Cossart P, Pizarro-Cerda J.
Infect Immun. 2010 Jan;78(1):204-9. Epub 2009 Nov 9.

2. Human BAHD1 promotes heterochromatic gene silencing.
Bierne H, Tham TN, Batsche E, Dumay A, Leguillou M, Kernéis-Golsteyn S, Regnault B, Seeler JS, Muchardt C, Feunteun J, Cossart P.
Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13826-31. Epub 2009 Aug 3.

3. Septins regulate bacterial entry into host cells.
Mostowy S, Nam Tham T, Danckaert A, Guadagnini S, Boisson-Dupuis S, Pizarro-Cerdá J, Cossart P.
PLoS One. 2009;4(1):e4196. Epub 2009 Jan 15.

4. Histone modifications induced by a family of bacterial toxins.
Hamon MA, Batsché E, Régnault B, Tham TN, Seveau S, Muchardt C, Cossart P.
Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13467-72. Epub 2007 Aug 3. Erratum in: Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17555.

5. A FRET analysis to unravel the role of cholesterol in Rac1 and PI 3-kinase activation in the InlB/Met signalling pathway.
Seveau S, Tham TN, Payrastre B, Hoppe AD, Swanson JA, Cossart P.
Cell Microbiol. 2007 Mar;9(3):790-803. Epub 2006 Nov 28.

Updated on 12/05/2014



Lab address

Unité Interactions Bactéries-Cellules

Institut Pasteur
25, Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE


Phone: + 33 (1) 45 68 88 41

Secretary: + 33 (1) 40 61 30 32

Fax: + 33 (1) 45 68 87 06


Our laboratory is located on the ground floor at the 53C entrance of the Roux Building (25, rue du Docteur Roux)

The metro stations Pasteur (line 6) and Volontaires (line 12) are within a 5 min walking distance from the Pasteur Institute.

The bus stop Pasteur (bus 95, towards Porte de Vanves) is located next to the Pasteur Institute main entrance.

For more information: Pasteur Institute Access and Paris Metro/Bus/Tram