The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
The mission of the Industrial Partnership team is to detect, promote, assist and protect the inventive activities from research (inventions, know-how and biological materials) conducted at the Institut Pasteur (and in some Institutes of its international network), and transfer there to industrial and/or institutional partners, in order to serve the patient needs and for the benefit of the society, as well as to contribute to sustainability of the Institut Pasteur’s resources.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
Javier PIZARRO-CERDAProfessional address :
Bacteria-cell interactions Unit – INSERM U604 – INRA USC2020
Department of Cell biology and Infection
25 rue du Docteur Roux -75724 PARIS Cedex 15-France.
Present position and status: Research Associate, Institut Pasteur
UNIVERSITY EDUCATION 1998 Ph.D. in Immunology, Centre d’Immunologie de Marseille/Luminy, France 1995 Master in Immunology (DEA), Centre d’Immunologie de Marseille-Luminy, France. 1994 Master in Biology (National University, Heredia- Costa Rica) 1989 Bachelor in Biology (University of Costa Rica – San José, Costa Rica)
RESEARCH EXPERIENCE 2001-Present Research Assistant, Unité des Interactions Bactéries-Cellules, Institut Pasteur, Paris, France. " Membrane dynamics during invasion of target cells by Listeria monocytogenes". February 2004 Visiting researcher, University of Texas Southwestern Medical Center, Dallas, USA. "Small Interfering RNAs assays". 1999-2001 Post-doctoral Fellow, Unité des Interactions Bactéries-Cellules, Institut Pasteur, Paris, France. "Proteomics of vacuolar compartments containing Listeria monocytogenes". Novembre 1999 Visiting researcher, Weizmann Institute, Rehovot, Israel. "Quantitative Confocal Microscopy of Bacterial Invasion". October 1997 Visiting researcher, University of Queensland, Brisbane, Australia. "Electron Microscopy of Bacterial Invasion". 1995-1998 Ph.D. in Immunology, Centre d’Immunologie de Marseille/Luminy, France. "Intracellular trafficking of Brucella abortus in mammalian non-phagocytic cells". 1994-1995 Master in Immunology (DEA), Centre d’Immunologie de Marseille-Luminy, France. "Intracellular trafficking of Brucella abortus LPS in macrophages". 1990-1994 Master in Biology, National University, Heredia, Costa Rica. "Activity of cationic peptides on Brucella abortus cell envelope".
TEACHING EXPERIENCE 2004 Intracellular Pathogens and Phagocytosis Course, AMSUD-Pasteur/EMBO, Mendoza, Argentina. 2002 Molecular and Cellular Microbiology Course, AMSUD-Pasteur Regional Course, Rosario, Argentina. "Bacterial and cellular factors involved in Listeria monocytogenes motility". Theoretical lectures and practical laboratory courses.
ORAL COMMUNICATIONS 2005 "Strategies for cell invasion by Listeria monocytogenes". Umea University, Department of Molecular Biology, Umea, Sweden. 2005 "Role of type II PI4-kinases during Listeriamonocytogenes invasion of target cells". Gordon Conference: Molecular Mechanisms of Microbial Adhesion, Salve Regina University, Newport, Rhode Island, USA. 2005 "Septin 9, a new cellular effector modulating cell invasion by Listeria". European Initiative for Microbiology and Infectious Diseases, Karolinska Institute, Stockholm, Sweden. 2004 "Involvement of PI4-kinase II in Listeria monocytogenes invasion". University of Texas, Department of Physiology, Dallas, USA. 2000 "Interaction of Listeria monocytogenes with mammalian cells". 4th Annual Meeting French Society for Microscopy. National Institute of Applied Sciences, Toulouse, France. 1999 "Exploitation of the cell resources by intracellular parasites". National Parliament, San José, Costa Rica. 1999 "Brucella survival within non-professional phagocytes." Hebrew University Medical School, Jerusalem, Israel. 1998 "Intracellular trafficking of Brucella abortus in host cells". Meeting: The Immune System and its Encounters with Tropical Pathogens, Karolinska Institute Training Program, Puntarenas, Costa Rica. 1997 "Retrograde transport of Brucella abortus in HeLa cells". University of Queensland, Department of Cell Biology, Brisbane, Australia. 1996 "Brucella abortus: association to non-professional phagocytes". Centre d’Immunologie de Marseille-Luminy, France.
GRANTS 2000: French Ministry for National Education, Research and Technology Grant in Microbiology. "Identification of proteic and lipidic components of Listeria internalisation vacuoles".
AWARDS 1999: Costarrican National Award for Science and Technology ‘Clodomiro Picado Twight’.
CONSULTING ACTIVITY 2004-Present Consulting Expert for the USA-Israel Binational Agricultural Research and Development Fund.
SELECTED PUBLICATION LIST 1. Pizarro-Cerdá, J, and Cossart, P. 2006. Subversion of cellular functions by Listeria. J. Pathol. 28, 215-223. 2. Dussurget, O, Pizarro-Cerdá, J, and Cossart, P. 2004. Molecular determinants of Listeria monocytogenes virulence. Annu. Rev. Microbiol. 58, 587-610. 3. Pizarro-Cerdá, J, and Tedin, K.. 2004. The bacterial signal molecule, ppGpp, regulates Salmonella virulence gene expression. Mol. Microbiol. 52, 1827-1844. 4. Pizarro-Cerdá, J, and Cossart, P. 2004. Subversion of phosphoinositide metabolism by intracellular bacterial patoghens. Nat. Cell Biol. 6, 1026-1033. 5. Pizarro-Cerdá, J, Jonquières, R, Gouin, E, Garin, J, Vandeckerkove, J, and Cossart, P. 2002. Distinct protein patterns associated with InlA- and InlB-phagosomes. Cell. Microbiol. 4, 101-115. 6. Jonquières, R, Pizarro-Cerdá, J, and P. Cossart. 2001. Synergy between N- and C-terminal domain of InlB for efficient invasion of non-phagocytic cells by Listeria monocytogenes. Mol. Microbiol. 42, 955-965. 7. Lecuit, M, Hurme, R, Pizarro-Cerdá, J, Ohayon, H, Geiger, B, and Cossart, P. 2000. A role for alpha- and beta-catenins in bacterial uptake. Proc. Natl. Acad. Sci. U.S.A. 97, 10008-10013. 8. Pizarro-Cerdá, J, Akira, S, Desjardins, M, Moreno, E, and Gorvel, JP. 1999. Endocytosis modulation in activated NF-IL6 (-/-) macrophages is responsible for a high susceptibility to B. abortus infection. J. Immunol. 162, 3519-3526. 9. Pizarro-Cerdá, J, Moreno, E, Sanguedolce, V, Mège, JL, and Gorvel, JP. 1998. Virulent Brucella abortus avoids lysosome fusion and distributes within autophagosome-like compartments. Infect. Immun. 66, 2387-2392. 10. Pizarro-Cerdá, J, Méresse, S, Parton, RG, van der Goot, G, Sola-Landa, A, Lopez-Goni, I, Moreno, E, and Gorvel, JP. 1998. Pathogenic Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of non-professional phagocytes. Infect. Immun. 66, 5711-5724.
Updated on 12/05/2014
Unité Interactions Bactéries-Cellules
INSERM U604 INRA USC2020
25, Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE
Phone: + 33 (1) 45 68 88 41
Secretary: + 33 (1) 40 61 30 32
Fax: + 33 (1) 45 68 87 06
Our laboratory is located on the ground floor at the 53C entrance of the Roux Building (25, rue du Docteur Roux)
The metro stations Pasteur (line 6) and Volontaires (line 12) are within a 5 min walking distance from the Pasteur Institute.
The bus stop Pasteur (bus 95, towards Porte de Vanves) is located next to the Pasteur Institute main entrance.