Research Interests - David Ribet

Ph.D.- Post-doctoral Fellow

Pubmed bibliographhy


Characterization of SUMOylations/deSUMOylations induced by Listeria monocytogenes and their roles in bacterial infection

My research studies are focused on the impact of Listeria monocytogenes on the SUMOylation machinery of the infected cell, and the impact of SUMOylation on infection. SUMOylation consists in the reversible modification of a target protein by the covalent fixation of an ubiquitin-like protein called SUMO. SUMO-modified proteins disclose altered properties and are involved in many essential cellular processes like regulation of transcription, nucleocytoplasmic transport, DNA repair, protein stability, and stress response. The impact of pathogenic bacteria like Listeria on these specific post-translational modifications remains yet completely unknown.

My aims are to identify cellular or bacterial proteins specifically SUMOylated or deSUMOylated upon infection by L. monocytogenes, and to understand the roles of these modifications in the life cycle of this pathogen.

Updated on 12/05/2014



Lab address

Unité Interactions Bactéries-Cellules

Institut Pasteur
25, Rue du Docteur Roux
75724 Paris Cedex 15 FRANCE


Phone: + 33 (1) 45 68 88 41

Secretary: + 33 (1) 40 61 30 32

Fax: + 33 (1) 45 68 87 06


Our laboratory is located on the ground floor at the 53C entrance of the Roux Building (25, rue du Docteur Roux)

The metro stations Pasteur (line 6) and Volontaires (line 12) are within a 5 min walking distance from the Pasteur Institute.

The bus stop Pasteur (bus 95, towards Porte de Vanves) is located next to the Pasteur Institute main entrance.

For more information: Pasteur Institute Access and Paris Metro/Bus/Tram