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A postdoctoral position is available in the Deriano lab (Lymphocyte Development & Oncogenesis) at the Institut Pasteur in Paris. Lymphoid cancers are among the most common human malignancies and characteristically harbor genomic aberrations. Metabolism of DNA double strand breaks during the programmed processes of antigen receptor diversification is a key common intermediate in the appearance of lymphoid neoplasm. We use mouse models and a combination of cellular-, molecular- and next generation sequencing-based approaches to better understand the mechanisms of genomic instability and tumor onset in developing lymphocytes.
Research Keywords - Cancer genomics, genome integrity, DNA repair, DNA damage, lymphocyte development, leukemia/lymphoma.
Context and environment - The Institut Pasteur is a world famous private non-profit foundation focused on the prevention and treatment of disease. The Institut Pasteur brings together three fields of activity - research, education and public health - on its campus with almost 2800 individuals. It is located in the center of Paris in France, in a both culturally and scientifically exciting environment (http://www.pasteur.fr/en).
Candidates should be highly motivated, committed and be willing to take on intellectual, scientific, technical and competitive challenges. The applicant should have a record of delivering high quality research and strong experience in the subjects of genome integrity, molecular biology, and/or cancer genetics/genomics. Experience in NGS techniques and data analysis and/or comparative genomics, computational biology, bioinformatics is highly desirable.
Contract: one-year, renewable (ERC funding). Salary based on experience.
To apply: Applicants should send a cover letter with a statement of research experience and interests and a C.V. with publications to Ludovic Deriano (firstname.lastname@example.org)