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  • Press release | 12.12.2014

    Malaria: formal identification of the artemisinin resistance gene

    Together with teams from Columbia University (USA), CNRS in Toulouse and NIH/NIAID (USA), Institut Pasteur scientists based in Paris and Cambodia have recently provided the key demonstration that K13 is indeed the main determinant of artemisinin resistance in Plasmodium falciparum parasites. This work is a landmark for the scientific community, as it provides a validated molecular marker for artemisinin resistance, which currently poses a major public health problem. This work is published in the journal Science.

  • © Institut Pasteur

    Press release | 04.12.2014

    Institut Pasteur Graduation Ceremony 2014

    The Institut Pasteur will host on the 12th of December 2014  the 2nd ceremony in honor of its graduating PhD class, with the  Doctors having defended in 2013-2014. This ceremony will be chaired by Pr Christian Bréchot, President of the Institut Pasteur. It will be held in presence of Jean-Philippe Pierre, deputy mayor of the 15th arrondissement of Paris.

  • Press release | 27.11.2014

    Ebola: a new Institut Pasteur is soon to be created in Guinea

    Pr Christian Bréchot, President of the Institut Pasteur, will be in Guinea Friday 28th November 2014, alongside François Hollande, President of the French Republic. Two agreements will be signed, one with the government of Guinea and the other one with the French Agency for Development (AFD), allowing for the creation of a new Pasteur Institute in Conakry in late 2016. On Saturday 29th, Pr. Bréchot will visit the Macenta treatment Center where the Institut Pasteur is setting-up a diagnostic laboratory.

  • Chikungunya virus particles on the surface of an infected cell  © Institut Pasteur/Thérèse Couderc

    Press release | 20.11.2014

    Chikungunya fever: Themis Bioscience’s vaccine candidate successful in phase 1

    The induction of neutralizing antibodies by a prophylactic Chikungunya vaccine candidate has now been confirmed by the final results of a phase 1 clinical trial, as well as its tolerability and safety. Detailed information of the trial has been presented at two international conferences. The vaccine candidate was developed under a R&D collaboration between Themis Bioscience GmbH and the Institut Pasteur (Paris) based upon a measles vaccine vector technology.

  • Press release | 13.11.2014

    Sanofi - Institut Pasteur Awards 2014

    Sanofi and the Institut Pasteur awarded on November 13th the Sanofi - Institut Pasteur awards for the third consecutive year. Four internationally renowned researchers were honored today for their work carried out in two major fields concerning world health: neglected tropical diseases and immunology. In 2014, the program set aside a total of 300.000 euros

  • Disk diffusion antibiogram of a clinical strain of Klebsiella pneumoniae, A bioinformatics tool to monitor the resistance and virulence of Klebsiella pneumoniae bacteria, © Institut Pasteur

    Press release | 28.10.2014

    A bioinformatics tool to monitor the resistance and virulence of Klebsiella pneumoniae bacteria

    By sequencing the genomes of several strains of Klebsiella pneumoniae, scientists have revealed their genetic profile and pinpointed the genes responsible for their multiple antibiotic resistance and virulence. They have used these results to compile a database for the scientific community, providing high-resolution genetic fingerprints and information on genes of medical importance. This should make it easier to monitor Klebsiella pneumoniae outbreaks.

  • Papillomavirus,  Human papillomavirus linked to auto-immune disease, © Institut Pasteur

    Press release | 14.10.2014

    Human papillomavirus linked to auto-immune disease

    Erosive oral lichen planus (OLP) is an auto-immune disease affecting skin and mucous membranes which results in an abnormal immune response against mucocutaneous cells. Today, scientists have proven that the immune cells involved in OLP are the same as those activated during an immune response to human papillomavirus (type HPV-16). This suggests a link between OLP and HPV.

  • Pseudomonas aeruginosa,  © Institut Pasteur

    Press release | 07.10.2014

    Cystic fibrosis: how a bacterium manipulates its host to eradicate an opponent

    The main cause of death in patients suffering from cystic fibrosis is respiratory infection caused by different bacterial populations, which vary according to the age of the patient. Scientists at the Institut Pasteur and Inserm have identified a novel mechanism used by the Pseudomonas aeruginosa bacterium to hijack the immune system of its host in order to eradicate another bacterium, Staphylococcus aureus ("golden staph"), and take its place in airways.

  • The three-dimensional structure of SUB1, Highly regulated therapeutic target shows promise in the search for new antimalarial treatments, © Jean-Christophe Barale, Institut Pasteur

    Press release | 10.09.2014

    Highly regulated therapeutic target shows promise in the search for new antimalarial treatments

    Artemisinin is currently the most effective malarial treatment available. However, the recent emergence in South-East Asia of artemisinin-resistant parasites strengthens the urgent need to identify a new generation of antimalarial drugs. In this context, scientists have determined the three-dimensional structure of a promising new therapeutic target for malaria: SUB1.

  • A neuron seen under fluorescence microscopy, Autism: SHANK gene may indicate the severity of the disorder, © Institut Pasteur

    Press release | 04.09.2014

    Autism: SHANK gene may indicate the severity of the disorder

    Thanks to a large-scale study conducted on nearly 1,000 autistic patients, scientists succeeded in mapping the clinical incidence and impact of certain genetic mutations linked to the cognitive and intellectual abilities of the patients. Mutations affecting the SHANK3 gene were shown to coincide with the most severe cases of autism and are associated with 1 out of 50 children with autism and intellectual deficits.

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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

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