The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
The mission of the Industrial Partnership team is to detect, promote, assist and protect the inventive activities from research (inventions, know-how and biological materials) conducted at the Institut Pasteur (and in some Institutes of its international network), and transfer there to industrial and/or institutional partners, in order to serve the patient needs and for the benefit of the society, as well as to contribute to sustainability of the Institut Pasteur’s resources.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
When the body receives an injury to the skin, a signal is sent to the brain, which generates a sensation of pain. Researchers have studied lesions in patients with Buruli ulcer, a tropical disease. They show that, despite the extent and severity of these wounds, they are less painful than others that seem relatively minor (e.g. scratches, low-degree burns). They discovered an analgesic mechanism that limits the transmission of pain signals to the brain. An understanding of this mechanism may be useful in developing new drugs for pain relief.
Call for applications: Scientists specialized in Microbiology
Institut Pasteur is seeking to reinforce its position by recruiting outstanding scientists (including clinicians) specialized in microbiology (virologists, bacteriologists). Major areas that we want to strengthen are vector-borne diseases (viral and bacterial), vaccine-preventable diseases (whooping cough, diphtheria, papillomaviruses), anaerobes, antimicrobial drug resistance.
Mild hearing impairment may indicate greater underlying problems
Scientists identified mice models that mimic high-frequency hearing impairment in humans. Their work sheds light on the anomalies causing the hearing impairment and could explain the pronounced masking effect experienced by some hearing-impaired individuals when trying to discriminate high-frequency sounds in noisy environments. The scientists suggest that more substantial auditory assessments would enable clinicians to improve diagnosis of these auditory impairments.
Scientists have recently demonstrated the existence of immunological memory cells in fetuses. These cells are developed in utero and are capable of producing an inflammatory-type immune response. The results of this study suggest that it may be possible to develop vaccine-induced immunological memory, during pregnancy and specific to the fetus, which would increase immunity in infants during the first months of life.
The Institut Pasteur is pleased to open the call for application for the 2014 Dedonder Clayton Award. This Award will honor scientists in Africa and Asia whose outstanding research is decisive to progress in public health, specifically in the field of research on HIV / AIDS and related infections. This Prize is awarded by Pr Christian BRECHOT, President of the Institut Pasteur and Pr Françoise Barré-Sinoussi, Nobel Prize in Medicine in 2008, and a jury representatives of the Institut Pasteur International Network and the ANRS. The Dedonder Clayton Prize is awarded every year since 2011.
The application will be a letter of intent (1 page recto / verso maximum) outlining the objectives, the schedule of accomplishments, the composition of the team and investigators, issues and outcomes of the project and a provisional budget. This letter of intent will be sent by email.
Deadline to submit applications: Monday, 30th June, 2014.
Elucidating the pathogenic mechanism of meningococcal meningitis
Neisseria meningitidis, also called meningococcus, is a bacterium responsible for meningitis and septicemia. Its most serious form, purpura fulminans, is often fatal. This bacterium, which is naturally present in humans in the nasopharynx, is pathogenic if it reaches the blood stream. Scientists have deciphered the molecular events through which meningococci target blood vessels and colonize them. This work opens a path to new therapeutic perspectives for treating vascular problems caused by this type of invasive infection.
Researchers have discovered that the immediate environment of stem cells can have a strong influence on the fate of their descendants : they observed that the forces applied to stem cells during division influenced the likelihood that these dividing cells would produce two new stem cells, one stem cell and one specialized cell, or even two specialized cells. This study has major implications for the therapeutic use of stem cells: it suggests that, by controlling the composition and conditions in the microenvironment of the niche, it is possible to reproduce and retain stem cell properties in culture for subsequent use in transplants to repair damaged tissues.
The Institut Pasteur in Paris announces an international call for midcareer candidates to establish a research group in epigenetics.
Successful applicant will be integrated into the cutting edge interdisciplinary environment offered by an internationally renowned institute combining fundamental and translational research, in an attractive location in central Paris, in close proximity to other major research centers. Candidates specializing in the field of DNA methylation, chromatin modifications, chromatin remodelling, non coding RNAs, long range interactions or inheritance of epigenetic traits are encouraged to apply.