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  • A section of lungs infected with influenza virus. Calpains, key cellular enzymes for fighting influenza. (c) Mustapha Si-Tahar/Inserm

    Press release | 16.02.2016

    Calpains, key cellular enzymes for fighting influenza

    Why not fight the influenza virus by blocking the cellular machinery it uses for replication? Researchers tested this hypothesis by specifically targeting the calpains, proteases involved in inflammatory mechanisms. Their results, obtained in animals, show that inhibiting these enzymes can not only reduce the symptoms of the disease, but also prevent infection by seasonal or pandemic influenza viruses.

  • Birdy: assessing the impact of resistant bacterial infections in young children

    International News | 15.02.2016

    Birdy: assessing the impact of resistant bacterial infections in young children

    The research program BIRDY is focused on bacterial infections, including resistant, in small children. On the occasion of the publication in The Lancet of a correspondence calling for accelerated efforts in research and public health in the fight against neonatal bacterial infection and antibiotic resistance in low-income countries, Dr. Awa Ndir, epidemiologist at the Institut Pasteur in Dakar (Senegal) and project coordinator, answers our questions.

  • Institutional | 15.02.2016

    Registration open for the Institut Pasteur neuroscience MOOC

    Registration opened today for a third Institut Pasteur MOOC (massive online open course), entitled "From neuron to behavior". The course will be available starting May 16th via the "France Université Numérique" (FUN) platform. This MOOC will cover cutting-edge topics in neuroscience research: evolution, development, plasticity and pathologies of the nervous system. 

    Register now for the Institut Pasteur neuroscience MOOC!

  • Tissue infected by Listeria (bacteria appear in red). YH Tsai, M Lecuit. Listeria: hypervirulent strains with cerebral and placental tropism. © Institut Pasteur.

    Press release | 01.02.2016

    Listeria: hypervirulent strains with cerebral and placental tropism

    Researchers recently published a large-scale study based on almost 7,000 strains of Listeria monocytogenes — the bacterium responsible for human listeriosis, a severe foodborne infection. Through the integrative analysis of epidemiological, clinical and microbiological data, the researchers have revealed the highly diverse pathogenicity of isolates belonging to this bacterial species. Comparative genomics led them to discover new virulence factors, which were demonstrated experimentally as involved in cerebral and fetal-placental listeriosis.

  • Research | 01.02.2016

    How does Legionella pneumophila, the bacterium causing legionellosis, use the host cell machinery to its own advantage?

    During analysis of its genome sequence, the team from the Biology of Intracellular Bacteria Unit (Institut Pasteur/CNRS), headed by Carmen Buchrieser, identified genes coding for proteins that were predicted to be involved in the infection of human cells. These proteins resemble proteins of higher organisms (eukaryotes), including humans, and can modify the physiology of the infected host cells. They are thus potential virulence factors. In this study, published in the journal PNAS, the researchers show that one of these proteins is secreted in the human cell and helps to block the antibacterial response of the infected cells.

  • Colonies of M. canettii and M. tuberculosis. © Roland Brosch, Institut Pasteur

    Press release | 27.01.2016

    Tuberculosis: discovery of a critical stage in the evolution of the bacillus towards pathogenicity

    It is the disappearance of a glycolipid from the bacterial cell envelope during evolution that may have considerably increased the virulence of tuberculosis bacilli in humans. Scientists have shown that this disappearance modified the surface properties of Mycobacterium tuberculosis, favoring its aggregation in "cords" and increasing its pathogenicity. These findings, which enable a better understanding of the mechanisms linked to the evolution and emergence of tuberculosis bacilli, constitute a major advance in our knowledge on this disease.

  • International News | 20.01.2016

    A new yellow fever vaccines production facility: AFD grants 6.5 million euros to the Institut Pasteur in Dakar Foundation

    In January 19, 2016 in Dakar a € 6.5 million financing agreement was signed, for the construction and equipment of an over 3000 m2 new yellow fever vaccine production facility, in the presence of His Excellency Jean-Félix- Paganon, French Ambassador to Senegal; Laurence Hart, Director of the French Development Agency (AFD) in Senegal and Professor André Spiegel, Director of the Institut Pasteur Foundation in Dakar (FIPD).

    Without treatment, vaccination is the only way to fight against yellow fever. Today, the number of produced vaccines is insufficient to meet the needs of populations in endemic countries. This project will enable the FIPD, pre-qualified by WHO for the production of this vaccine, to develop responses activities against epidemics, to monitoring surveillance of arboviruses and viral hemorrhagic fever and to intensify training.

  • Dannemann et al./American Journal of Human Genetics 2016

    Press release | 08.01.2016

    Neanderthal genes gave modern humans an immunity boost, allergies

    When modern humans met Neanderthals in Europe and the two species began interbreeding many thousands of years ago, the exchange left humans with gene variations that have increased the ability of those who carry them to ward off infection. This inheritance from Neanderthals may have also left some people more prone to allergies. The discoveries add to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infection.

  • Aedes aegypti mosquito. © Institut Pasteur

    Press release | 08.01.2016

    The Institut Pasteur in French Guiana publishes the first complete genome sequence of the Zika virus circulating in the Americas

    Having confirmed the first cases of infection in Suriname then in French Guiana, the Institut Pasteur in French Guiana has sequenced the complete genome of the Zika virus, which is responsible for an unprecedented epidemic currently sweeping through the tropical regions of the Americas. Published in The Lancet medical journal today, the analysis of this sequence shows almost complete homology with the strains responsible for the epidemic that occurred in the Pacific in 2013 and 2014.

  • Jacques Ravel. Institut Pasteur

    Press release | 07.01.2016

    University of Maryland School of Medicine researcher Jacques Ravel receives prestigious international science award

    Jacques Ravel, PhD, Professor of Microbiology and Immunology, as well as Associate Director for Genomics at the Institute for Genome Sciences (IGS), both at the University of Maryland School of Medicine, has been named a 2015-2017 Blaise Pascal International Research Chair, one of the most prestigious European science awards. He is spending this year working at the Institut Pasteur in Paris, and over the next two years will divide his time between Paris and Baltimore. He focuses on the human microbiome and its role in women’s health.

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Pasteur museum

Welcome to Pasteur Museum


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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

Pasteur Museum