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  • International | 26.06.2014

    Second wave of Ebola in Africa: the Institut Pasteur in Dakar is in the first line

    SECOND WAVE OF EBOLA IN AFRICA: THE INSTITUT PASTEUR IN DAKAR IS IN THE FIRST LINE
    Since March 21, date of the declaration of the outbreak of Ebola in Guinea, the Institut Pasteur from the Africa Region and particularly the Institut Pasteur in Dakar in collaboration with partners, face up to a deadly Ebola epidemic second wave.
    The point of the situation in Guinea of June, 15th shows that 3 new areas were added to the two former (Kouroussa, Télimélé and Boffa districts). Today, the number of cases recorded is 376 including 241 deaths. If the epidemic’s epicenter lies in the forested area around the city of Guéckédou (southern Guinea) it extends to Sierra Leone (Kailahun) and Liberia (Lofa).

    From the beginning of the epidemic, WHO entrusted the mission to the Institut Pasteur in Dakar for epidemiological surveillance in Conakry and in the districts area of French Guinea. For almost three months, a team of four experts under the direction of Dr. Amadou Sall, Head of the WHO Collaborating Centre on hemorrhagic fevers in Institut Pasteur in Dakar, works in the field to detect new cases, to confirm the diagnosis and to monitor disease. The Institut Pasteur in Côte d'Ivoire alongside the Institut Pasteur in Dakar has strengthened territory surveillance actions. This monitoring process is consolidated by several actions towards the population i.e.: communication, coverage of patients and funerals, health education and the provision of psychological and social support.
    The Institut Pasteur in Côte d'Ivoire provided oversight of the epidemic in Côte d'Ivoire in developing the diagnostic in the border with Guinea.
     
    Ebola is a viral disease. Today, five types of Ebola virus were identified. The virus outbreak in Guinea is close to the Ebola virus responsible for the outbreak in 1976 in Zaire.
    Identified reservoir of the disease is a bat (R. aegyptiacus) which infects monkeys, cattle and men. At this stage, the transmission is person to person.
    Incubation ranges vary from 2 to 21 days and presents 23 to 88% of mortality, around 7 to 10 days after the symptoms. The virus is present in the blood (7-10 days), sperm (> 3 months), secretions, fluids (tears, sweat). Infectious period is the stage of overt disease. To date, there is no specific treatment or available vaccine to fight the Ebola virus. The prevention passes through effective monitoring and management of epidemics.

  • Africa Regional Meeting of the Institut Pasteur International Network

    International News | 26.06.2014

    Africa Regional Meeting of the Institut Pasteur International Network

    The Africa regional meeting of the Institut Pasteur International Network was organized in the Institut by Dakar (Senegal) from June 18th to June 19th followed by a Scientific Day of the African Institutes June 20th, 2014.

    This regional meeting and the scientific Day of Instituts Pasteur in the Africa region was an opportunity to discuss new research strategies in the Institutes of the Network, from bioinformatics till biostatistics, the Center for Global Health and biomedical resources. The challenges posed by infectious diseases on this continent such as rabies, malaria and hepatitis have been developed in workshops. Finally the issues of monitoring antiretroviral and antimalarial resistance were discussed by experts from the African region.

  • Scientists discover a novel mechanism in the development of pre-eclampsia © Institut Pasteur

    Research | 23.06.2014

    Scientists discover a novel mechanism in the development of pre-eclampsia

    No treatment currently exists for pre-eclampsia, a gestational disorder which affects over 8 million pregnant women worldwide and can cause premature delivery or death of the mother or the fetus.

  • Can injuries to the skin be painless? National Buruli ulcer control Programme, Benin ©OMS

    Press release | 19.06.2014

    Can injuries to the skin be painless?

    When the body receives an injury to the skin, a signal is sent to the brain, which generates a sensation of pain. Researchers have studied lesions in patients with Buruli ulcer, a tropical disease. They show that, despite the extent and severity of these wounds, they are less painful than others that seem relatively minor (e.g. scratches, low-degree burns). They discovered an analgesic mechanism that limits the transmission of pain signals to the brain. An understanding of this mechanism may be useful in developing new drugs for pain relief.

     

  • Jobs | 17.06.2014

    Call for applications: Scientists specialized in Microbiology

    Institut Pasteur is seeking to reinforce its position by recruiting outstanding scientists (including clinicians) specialized in microbiology (virologists, bacteriologists). Major areas that we want to strengthen are vector-borne diseases (viral and bacterial), vaccine-preventable diseases (whooping cough, diphtheria, papillomaviruses), anaerobes, antimicrobial drug resistance.

  • Jobs | 16.06.2014

    To further develop the Center for Global Health (CGH), Institut Pasteur Paris is hiring a Deputy Director

    This position offers a unique opportunity to be actively involved in the development and the implementation of the CGH.

  • Hair bundles of the auditory outer hair cells - Mild hearing impairment may indicate greater underlying problems - © Institut Pasteur

    Press release | 12.06.2014

    Mild hearing impairment may indicate greater underlying problems

    Scientists identified mice models that mimic high-frequency hearing impairment in humans. Their work sheds light on the anomalies causing the hearing impairment and could explain the pronounced masking effect experienced by some hearing-impaired individuals when trying to discriminate high-frequency sounds in noisy environments. The scientists suggest that more substantial auditory assessments would enable clinicians to improve diagnosis of these auditory impairments.

  • Découverte d'une mémoire immunitaire chez le foetus - Institut Pasteur

    Press release | 10.06.2014

    Immunological memory discovered in fetuses

    Scientists have recently demonstrated the existence of immunological memory cells in fetuses. These cells are developed in utero and are capable of producing an inflammatory-type immune response. The results of this study suggest that it may be possible to develop vaccine-induced immunological memory, during pregnancy and specific to the fetus, which would increase immunity in infants during the first months of life.

     

  • Appel à candidature Prix Dedonder Clayton 2014

    International | 03.06.2014

    Call for application: Dedonder Clayton Award 2014

    The Institut Pasteur is pleased to open the call for application for the 2014 Dedonder Clayton Award. This Award will honor scientists in Africa and Asia whose outstanding research is decisive to progress in public health, specifically in the field of research on HIV / AIDS and related infections. This Prize is awarded by Pr Christian BRECHOT, President of the Institut Pasteur and Pr Françoise Barré-Sinoussi, Nobel Prize in Medicine in 2008, and a jury representatives of the Institut Pasteur International Network and the ANRS. The Dedonder Clayton Prize is awarded every year since 2011.

    The application will be a letter of intent (1 page recto / verso maximum) outlining the objectives, the schedule of accomplishments, the composition of the team and investigators, issues and outcomes of the project and a provisional budget. This letter of intent will be sent by email.

    Deadline to submit applications: Monday, 30th June, 2014.
     

     

    For all questions

     

     

    See the website

     

     

  • Colonization of brain vessels by N. meningitidis

    Research | 02.06.2014

    Elucidating the pathogenic mechanism of meningococcal meningitis

    Neisseria meningitidis, also called meningococcus, is a bacterium responsible for meningitis and septicemia. Its most serious form, purpura fulminans, is often fatal. This bacterium, which is naturally present in humans in the nasopharynx, is pathogenic if it reaches the blood stream. Scientists have deciphered the molecular events through which meningococci target blood vessels and colonize them. This work opens a path to new therapeutic perspectives for treating vascular problems caused by this type of invasive infection.

     

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