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  • Institut Pasteur

    Press release | 25.11.2016

    Christian Vigouroux elected as Chairman of the Institut Pasteur Board of Directors

    The new Institut Pasteur Board of Directors held its first meeting on November 24, 2016 and elected as its Chairman French Council of State Department Head Christian Vigouroux. Christian Vigouroux takes over from Rose-Marie Van Lerberghe.

  • Press release | 04.11.2016

    Malaria – Discovery of a molecular marker associated with piperaquine resistance in parasites

    Scientists have identified a molecular marker able to detect Plasmodium falciparum malaria parasites resistant to piperaquine, a drug currently used in combination with artemisinin derivatives in the latest generation of antimalarial treatments recommended by the WHO. This discovery should pave the way for rapid monitoring strategies and enable public health policy makers to recommend effective antimalarial treatments adapted to the local epidemiological situation.

  • The specific VHH antibody for plaques. © Institut Pasteur

    Press release | 03.11.2016

    Diagnosis of Alzheimer's disease: llama antibodies detect cerebral lesions

    The major challenge facing physicians treating Alzheimer's is the ability to detect markers of the disease as early as possible. These markers, located in the brain, are difficult to access, hampering diagnosis. Using two types of llama antibody capable of crossing the blood-brain barrier, scientists have developed a non-invasive approach to reach brain cells in a mouse model of the disease. Once in the brain, these llama antibodies can specifically mark and show amyloid plaques and neurofibrillary tangles, the two types of lesions that characterize Alzheimer's disease.

  • Illustration © Jérome Bon

    Press release | 21.10.2016

    Africans and Europeans have genetically different immune systems... and Neanderthals had something to do with it

    In a large-scale study, scientists from the Institut Pasteur and the CNRS unraveled the immune responses of 200 African and European individuals. They show that there is indeed a difference in the way these populations respond to infection, that this response is largely controlled by genetics, and that natural selection has played an important role in shaping such immune profiles.

  • Press release | 12.10.2016

    Press release following publication of an article in The Korea Times on October 5, 2016

    In an article published online in The Korea Times on October 5, 2016, serious accusations were made against the Institut Pasteur in Korea and the Institut Pasteur in Paris and its President.

  • Trypanosomes (Trypanosoma brucei brucei, fluorescent green) in the dermis of a mouse with no parasites in the bloodstream, 29 days after infection. Sleeping sickness: parasites found hiding in the skin. © Institut Pasteur

    Press release | 22.09.2016

    Sleeping sickness: parasites found hiding in the skin

    Scientists have demonstrated the presence of a large quantity of trypanosomes – the parasites responsible for sleeping sickness – in the skin of individuals with no symptoms. This discovery should refocus the screening strategy for this disease, which was previously based on the detection of parasites in the bloodstream, and raises the possibility of eliminating the disease in West Africa.

  • Localization of bacteria in the ileum of mice given a normal diet (left-hand image) and a high-fat diet (right-hand image). Too much fat rapidly disrupts the balance of the gut microbiota. © Institut Pasteur

    Press release | 19.09.2016

    Too much fat rapidly disrupts the balance of the gut microbiota

    A destabilizing factor such as a change in diet can disrupt the entire gut microbiota, with possible health consequences. An international study has recently demonstrated in mice that a high-fat diet has a direct influence on the gut microbiota and its environment. Bacterial communities react to this new diet with a massive reorganization, and the small intestine itself undergoes changes in its defense capacity – from the very first month.

  • Representation of space in the nicotinic receptor. Alzheimer's: nicotinic receptors as a new therapeutic target.  © Institut Pasteur

    Press release | 29.08.2016

    Alzheimer's: nicotinic receptors as a new therapeutic target

    Several scientific studies have indicated that nicotine may be beneficial for memory function. Scientists from the Institut Pasteur and the CNRS set out to shed further light on the properties attributed to nicotine – which is known to have an adverse effect on health – by determining the precise structure of the nicotinic receptors in the hippocampus region of the brain. Using mouse models for Alzheimer's disease, they identified the β2 subunit of the nicotinic receptor as a target that, if blocked, prevents the memory loss associated with Alzheimer's.

  • The Mycobacterium tuberculosis bacterium, causative agent of tuberculosis. Tuberculosis: a promising vaccine candidate. © Institut Pasteur

    Press release | 02.08.2016

    Tuberculosis: a promising vaccine candidate

    Scientists have published the results of their research into the action mechanisms of a promising experimental tuberculosis (TB) vaccine. BCG, the only currently approved TB vaccine, has been around for almost a century, but it is only partially effective and the protection it offers fades over time. Given the current emergence of adult TB cases in conjunction with the HIV epidemic and the rise in multidrug-resistant TB strains, the development of a new, more effective vaccine is a global health priority.

  • Anopheles stephensi infected by Plasmodium berghei

    Press release | 18.07.2016

    Malaria: a genetically attenuated parasite induces an effective, long-lasting immune response

    With nearly 3.2 billion people currently at risk of contracting malaria, scientists from the Institut Pasteur, the CNRS and Inserm have experimentally developed a live, genetically attenuated vaccine for Plasmodium, the parasite responsible for the disease. By identifying and deleting one of the parasite's genes, the scientists enabled it to induce an effective, long-lasting immune response in a mouse model. These findings were published in the Journal of Experimental Medicine on July 18, 2016.

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Pasteur museum

Welcome to Pasteur Museum


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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

Pasteur Museum