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  • Green monkey cells infected with Zika virus seen through a transmission electron microscope. Viral particles measure 40nm in diameter. How could Zika enter Europe? © Institut Pasteur

    Press release | 25.04.2016

    How could Zika enter Europe?

    Researchers at the Institut Pasteur have assessed the transmission potential of four populations of Aedes mosquitoes in circulation on the island of Madeira and southern France with a view to examining various possible scenarios for the introduction of Zika virus to Europe. Their work suggests that the Aedes aegypti mosquito present in Madeira is more likely to promote local transmission of Zika virus than Aedes albopictus. Consequently, it appears that the risk of a Zika epidemic in continental Europe is still low.

  • A Plasmodium parasite at the sporozoite stage. Malaria: a new route of access to the heart of the parasite. © Nassira Mahmoudi

    Press release | 11.04.2016

    Malaria: a new route of access to the heart of the parasite

    Scientists have just identified an Achilles heel in the parasite that causes malaria, by showing that its optimum development is dependent on its ability to expropriate RNA molecules in infected cells – a host-pathogen interaction that had never previously been observed.

  • Lluis Quintana-Murci, Scientific Director of the Institut Pasteur. © Giovanni Cittadini Cesi

    Press release | 23.03.2016

    Lluis Quintana-Murci appointed as Scientific Director of the Institut Pasteur

    On March 23, the Institut Pasteur announced that Lluis Quintana-Murci had been appointed as Scientific Director. This new position has been created in connection with the implementation of the general strategic plan adopted by the Institut Pasteur management. Lluis Quintana-Murci, a member of the Executive Board, will serve as the person of reference and coordinator for the Institut Pasteur's scientific teams. The aim is to facilitate the formalization and day-to-day implementation of the Institut Pasteur's scientific policies and to coordinate scientific evaluation activities and related action plans.

  • Colored image of Shigella, the agent of bacillary dysentery. A genomic study of epidemic dysentery: how Europe exported a scourge worldwide. © Institut Pasteur

    Press release | 21.03.2016

    A genomic study of epidemic dysentery: how Europe exported a scourge worldwide

    Scientists at the Institut Pasteur and its International Network, the Wellcome Trust Sanger Institute (Cambridge, United Kingdom) and several international institutions have just published an exceptionally wide-ranging study tracing the history of the bacillus responsible for epidemic dysentery – one of the worst scourges to afflict humans throughout the 18th and 19th centuries. This vast scientific investigation has uncovered hitherto unknown links between the various outbreaks that have occurred through history.

  • Zika and microcephaly: first trimester of pregnancy most critical. Institut Pasteur

    Press release | 16.03.2016

    Zika and microcephaly: first trimester of pregnancy most critical

    A new analysis of data from the 2013-2014 Zika epidemic in French Polynesia by scientists from the Institut Pasteur, Paris, and their French Polynesian colleagues has confirmed the incidence of grouped cases of microcephaly and quantified the risk of microcephaly associated with the virus. Using innovative mathematical modeling techniques, their research shows that the risk of microcephaly is around 1% for a fetus or newborn whose mother has been infected by the Zika virus during the first trimester of pregnancy.

  • DNA sequencing. © Institut Pasteur

    Press release | 07.03.2016

    Obesity: an epigenetic track to fight against weight gain and hypercholesterolemia

    The number of obesity cases has doubled since 1980: in 2014, over 600 million adults were affected across the world. The causes of this epidemic include unbalanced diet, as well as environmental and genetic factors. French researchers reveal that an epigenetic factor, the BAHD1 protein, participates in the regulatory mechanisms of cholesterol levels and weight gain. These results open new ways for finding therapies against obesity, diabetes and cardiovascular diseases.

  • Launch of the AFRIBIOTA research program: a new approach in the fight against child malnutrition. © Thomas Kesteman - Institut Pasteur Madagascar

    Press release | 07.03.2016

    Launch of the AFRIBIOTA research program: a new approach in the fight against child malnutrition

    More than 30 Madagascan and international scientists and clinicians met from March 7 to 9, 2016 at the Institut Pasteur in Madagascar for the official launch of the AFRIBIOTA project, an ambitious multidisciplinary research program to improve our understanding of chronic child malnutrition. The long-term aim of this innovative program, which combines fundamental and clinical research – especially research into the intestinal microbiota in children in conjunction with social science and neuroscience research – is to develop new diagnostic approaches that can be easily used in the field.

  •  On the left: Aedes aegypti mousquito, on the right: Aedes albopictus mousquito. © Institut Pasteur

    Press release | 04.03.2016

    Low competence of Aedes mosquitoes for Zika virus transmission

    The Institut Pasteur's Arboviruses and Insect Vectors Unit, led by Anna-Bella Failloux, has carried out a study on the vector competence of seven populations of Aedes aegypti and Aedes albopictus collected in Guadeloupe, French Guiana, Martinique, Brazil and the United States. The results, published in PLoS Neglected Tropical Diseases, show that, while Aedes aegypti and Aedes albopictus are both capable of becoming infected and replicating the virus in their body, they are not very competent when it comes to transmitting the Zika virus through a bite.

  • Lymphocytes infected with HIV-1. Antibodies capable of eliminating HIV-infected cells. © Olivier Schwartz and the Institut Pasteur Ultrapole.

    Press release | 03.03.2016

    Antibodies capable of eliminating HIV-infected cells

    Researchers have recently shown that some effective antibodies recognize cells infected by the human immunodeficiency virus (HIV) and trigger their destruction by the immune system. This discovery sheds new light on the mechanism of action of these specific antibodies, which are currently undergoing clinical trials.

  • Infected cells by the Zika virus in transmission electron microscopy. Zika: Confirmation of a causal link between the Zika virus and Guillain-Barré Syndrome. © Institut Pasteur.

    Press release | 01.03.2016

    Zika: Confirmation of a causal link between the Zika virus and Guillain-Barré Syndrome

    Using data collected in French Polynesia, researchers from the Institut Pasteur, the CNAM (Conservatoire national des arts et métiers), the Institut Louis Malardé, the French Polynesia Hospital Centre, and the Public Hospitals of Paris (AP-HP), have shown that infection by the Zika Virus (ZIKV) increases the likelihood of contracting Guillain-Barré Syndrome (GBS), a severe form of limb paralysis that is often accompanied by respiratory impairment. GBS has been observed in countries where the Zika epidemic is prolific.

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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

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