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  • Tissue infected by Listeria (bacteria appear in red). YH Tsai, M Lecuit. Listeria: hypervirulent strains with cerebral and placental tropism. © Institut Pasteur.

    Press release | 01.02.2016

    Listeria: hypervirulent strains with cerebral and placental tropism

    Researchers recently published a large-scale study based on almost 7,000 strains of Listeria monocytogenes — the bacterium responsible for human listeriosis, a severe foodborne infection. Through the integrative analysis of epidemiological, clinical and microbiological data, the researchers have revealed the highly diverse pathogenicity of isolates belonging to this bacterial species. Comparative genomics led them to discover new virulence factors, which were demonstrated experimentally as involved in cerebral and fetal-placental listeriosis.

  • Colonies of M. canettii and M. tuberculosis. © Roland Brosch, Institut Pasteur

    Press release | 27.01.2016

    Tuberculosis: discovery of a critical stage in the evolution of the bacillus towards pathogenicity

    It is the disappearance of a glycolipid from the bacterial cell envelope during evolution that may have considerably increased the virulence of tuberculosis bacilli in humans. Scientists have shown that this disappearance modified the surface properties of Mycobacterium tuberculosis, favoring its aggregation in "cords" and increasing its pathogenicity. These findings, which enable a better understanding of the mechanisms linked to the evolution and emergence of tuberculosis bacilli, constitute a major advance in our knowledge on this disease.

  • Dannemann et al./American Journal of Human Genetics 2016

    Press release | 08.01.2016

    Neanderthal genes gave modern humans an immunity boost, allergies

    When modern humans met Neanderthals in Europe and the two species began interbreeding many thousands of years ago, the exchange left humans with gene variations that have increased the ability of those who carry them to ward off infection. This inheritance from Neanderthals may have also left some people more prone to allergies. The discoveries add to evidence for an important role for interspecies relations in human evolution and specifically in the evolution of the innate immune system, which serves as the body's first line of defense against infection.

  • Aedes aegypti mosquito. © Institut Pasteur

    Press release | 08.01.2016

    The Institut Pasteur in French Guiana publishes the first complete genome sequence of the Zika virus circulating in the Americas

    Having confirmed the first cases of infection in Suriname then in French Guiana, the Institut Pasteur in French Guiana has sequenced the complete genome of the Zika virus, which is responsible for an unprecedented epidemic currently sweeping through the tropical regions of the Americas. Published in The Lancet medical journal today, the analysis of this sequence shows almost complete homology with the strains responsible for the epidemic that occurred in the Pacific in 2013 and 2014.

  • Jacques Ravel. Institut Pasteur

    Press release | 07.01.2016

    University of Maryland School of Medicine researcher Jacques Ravel receives prestigious international science award

    Jacques Ravel, PhD, Professor of Microbiology and Immunology, as well as Associate Director for Genomics at the Institute for Genome Sciences (IGS), both at the University of Maryland School of Medicine, has been named a 2015-2017 Blaise Pascal International Research Chair, one of the most prestigious European science awards. He is spending this year working at the Institut Pasteur in Paris, and over the next two years will divide his time between Paris and Baltimore. He focuses on the human microbiome and its role in women’s health.

  • Activation of the inflammasome. The mechanism of an AIDS vaccine candidate filmed in vivo. © Institut Pasteur

    Press release | 21.12.2015

    The mechanism of an AIDS vaccine candidate filmed in vivo

    Using innovative technology, scientists from the Institut Pasteur and Inserm have filmed in vivo the process by which an AIDS vaccine candidate, developed by the French Vaccine Research Institute and the ANRS, triggers the immune response. This previously unseen footage clearly shows how the vaccine recruits the immune cells needed to destroy infected cells. These results shed new light on the mode of action and potential of this vaccine.

  • Muscle tissue after sepsis. Sepsis: cell therapy to repair muscle long-term impairment. © Institut Pasteur

    Press release | 15.12.2015

    Sepsis: cell therapy to repair muscle long-term impairment

    Scientists have recently published a paper in which they reveal mayor players in the severe muscle damage caused by sepsis, or septicemia, which explains why many patients suffer debilitating muscle impairment long-term after recovery. They propose a therapeutic approach based on mesenchymal stem cell transplantation, which has produced encouraging results and has proved successful in restoring muscle capacity in animals.

  • A cell undergoing apoptosis, with apoptotic bodies and blebs typical of this type of cell death. © Institut Pasteur

    Press release | 14.12.2015

    How dying cells regulate immunity

    More than a million cells die every minute in an adult human body. But what actually happens to these cells? How does cell death influence all our living organs and tissues, particularly our immune system? Research into how the different types of cell death influence immunity is vital for the development of therapies based on immune system activation.

  •  Population of primary human macrophages infected with a HIV. © Institut Pasteur / Asier Saez-Cirion

    Press release | 09.12.2015

    Publication of the results of the first case of prolonged remission (12 years) in an HIV-infected child

    Last July has been a researcher presented the case of a young woman who was HIV-infected at birth via mother-to-child transmission and spent 12 years in virological remission, despite not having taken any antiretroviral therapy. This first case of long-term remission in a child, monitored in the French ANRS pediatric cohort, is described in an article published on December 9, in The Lancet HIV, whose main author is Dr Asier Sáez-Cirión.

  • Aka Pygmy, Central African Republic. © Serge BAHUCHET/MNHN/CNRS Photo Library.

    Press release | 30.11.2015

    Our epigenome is influenced by our habitat and lifestyle

    Research on the genomes of Pygmy hunter-gatherer populations and Bantu farmers in Central Africa, carried out by scientists from the Institut Pasteur and the CNRS in cooperation with French and international teams, has shown for the first time that our habitat and lifestyle can have an impact on our epigenome – the entire system that controls the expression of our genes without affecting their sequence.

     
     

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Pasteur museum

Welcome to Pasteur Museum


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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

Pasteur Museum