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  • Can injuries to the skin be painless? National Buruli ulcer control Programme, Benin ©OMS

    Press release | 19.06.2014

    Can injuries to the skin be painless?

    When the body receives an injury to the skin, a signal is sent to the brain, which generates a sensation of pain. Researchers have studied lesions in patients with Buruli ulcer, a tropical disease. They show that, despite the extent and severity of these wounds, they are less painful than others that seem relatively minor (e.g. scratches, low-degree burns). They discovered an analgesic mechanism that limits the transmission of pain signals to the brain. An understanding of this mechanism may be useful in developing new drugs for pain relief.

     

  • Hair bundles of the auditory outer hair cells - Mild hearing impairment may indicate greater underlying problems - © Institut Pasteur

    Press release | 12.06.2014

    Mild hearing impairment may indicate greater underlying problems

    Scientists identified mice models that mimic high-frequency hearing impairment in humans. Their work sheds light on the anomalies causing the hearing impairment and could explain the pronounced masking effect experienced by some hearing-impaired individuals when trying to discriminate high-frequency sounds in noisy environments. The scientists suggest that more substantial auditory assessments would enable clinicians to improve diagnosis of these auditory impairments.

  • Découverte d'une mémoire immunitaire chez le foetus - Institut Pasteur

    Press release | 10.06.2014

    Immunological memory discovered in fetuses

    Scientists have recently demonstrated the existence of immunological memory cells in fetuses. These cells are developed in utero and are capable of producing an inflammatory-type immune response. The results of this study suggest that it may be possible to develop vaccine-induced immunological memory, during pregnancy and specific to the fetus, which would increase immunity in infants during the first months of life.

     

  • Directing stem cells fates - Institut Pasteur

    Press release | 23.05.2014

    Directing stem cells fates

    Researchers have discovered that the immediate environment of stem cells can have a strong influence on the fate of their descendants : they observed that the forces applied to stem cells during division influenced the likelihood that these dividing cells would produce two new stem cells, one stem cell and one specialized cell, or even two specialized cells. This study has major implications for the therapeutic use of stem cells: it suggests that, by controlling the composition and conditions in the microenvironment of the niche, it is possible to reproduce and retain stem cell properties in culture for subsequent use in transplants to repair damaged tissues.

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The Pasteur Museum is located at the Institut Pasteur, situated at: 25 rue du Docteur Roux 75015 Paris, France
 

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