The Pasteur Museum is housed in the apartment where Louis Pasteur spent his final seven years and offers a rare behind-the-scenes look at the living and working environment of the world-renowned scientist. Visitors can gain a unique insight into his everyday life alongside his wife and can admire his rich and diverse scientific work.
The Institut Pasteur’s scientific strategy focuses on developing original and innovative topics and promoting interdisciplinary and multidisciplinary cooperation and approaches. The Institut Pasteur teams have access to the technological resources needed to speed up and further improve the quality of their outstanding research.
Ever since the introduction of the world’s first "Technical Microbiology" course in 1889, teaching has been a priority for the Institut Pasteur. The Institut Pasteur has an international reputation for quality teaching that attracts students from all over the world who come to further their training or top up their degree programs.
With international courses, PhD and postdoctoral traineeship, each institute of the Institut Pasteur International Network (RIIP) contributes to the transmission of knowledge with the training of young researchers all around the world. In this context, doctoral and postdoctoral programmes, study and traineeship fellowships are available to scientists. Alongside training, dynamism and attractiveness of RIIP will result in the creation of 4-year group for the young researchers.
A team from the Institut Pasteur working with the CNRS (French National Center for Scientific Research) has shown in an article published in the EMBO Journal that a yeast can be used as a cell model for a rare and severe neurodegenerative disease affecting adolescents. This discovery could provide researchers with an unexpected and particularly effective tool for studying the genetics of this pathology and that of other diseases linked to the degeneration of nerve cells.
Thanks to a strain of yeast mutated in the gene homolog to the one affected in SCAN1 patients, scientists have been able to identify similarities in the “symptoms” observed: yeasts deficient in this gene, program their own death when they do not divide, just like the nerve cells of patients.
“For 20 years, yeasts were recognized as efficient models of human cell division able to mimic the cancerization process. Today we are showing that, conversely, they can behave like neurons, i.e. cells that do not divide!”, explains Benoît Arcangioli. Development of such a model should therefore not only provide an original research tool for SCAN1, but also open up new avenues of exploration for other neurodegenerative diseases, such as Parkinson’s disease.