En application du plan Vigipirate l'accès à l'Institut Pasteur est subordonné à la présentation d'une pièce d'identité

17th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants
This conference focuses on the role of antioxidants as modulators of redox signaling pathways rather than players that counteract oxidative stress. Indeed, antioxidants affect cells signaling provided by redox processes. Mitochondria constitute localized signaling domains and produce reactive oxygen species, ROS (i.e. superoxide and hydrogen peroxide), which are signaling molecules generated by the respiratory chain. The conference will also focus on understanding the mechanisms by which cells respond to oxidative stress and prevent cell damage and cell death, with a particular interest in neurons and neurological conditions, stroke, Alzheimer’s disease, kidney, muscle, and liver pathologies. The mechanisms of redox regulation of cellular processes will also be discussed. Little is known on the specific targets of ROS and how oxidant and antioxidant signals are transmitted in the cell. To understand mechanisms of redox control and their role in oxidative stress pathologies and aging, it is necessary to identify and dissect the function of the key players of redox processes.
We aim that Paris Redox 2016 will contribute to a better understanding of redox control in physiological and pathological states and in ageing, leading to new therapeutic and disease-preventive agents.

A special registration fee (50% reduction) is previewed for scientists who work at the Institut Pasteur. Please contact Miria Ricchetti
Amphithéâtre Duclaux, Institut Pasteur - From 13 juin 2016 to 15 juin 2016

Contact: Miria Ricchetti (miria.ricchetti@pasteur.fr)

EMBO Conference: Problems of Listeriosis ISOPOL XIX Conference
The bacterium Listeria monocytogenes is responsible for severe food-borne infections that affect immunocompromised individuals, new born babies, elderly and pregant women. Mortality due to listeriosis is still close to 30%. Contamination by this organism leads to food recalls from the market. Listeria is also of veterinary imortance. Strikingly, three decades of molecular, and cellular studies have in addition raised Listeria among the best models in infection biology.

The EMBO conference ISOPOL XIX is the 19th edition of an international meeting which gathers every three years, participants from all over the world and allows exchange and update on a wide range of topics concerning Listeria and listeriosis from epidemiology, diagnostic, and typing methods, to genomics, post-genomics, fundamental microbiology, cell biology and pathogenesis.

The meeting intends to attract up to 450 participants. The target audience includes scientists including students and post docs, from the academy, from the industry and from public health agencies i.e. fundamental microbiologists, medical microbiologists, veterinary microbiologists and public health specialists as well as researchers in cell biology and immunology.

Online registration mandatory for Pastorians : 150 €
Institut Pasteur - CIS - From 14 juin 2016 to 17 juin 2016

Contact: Pascale COSSART (isopol2016@pasteur.fr)

EMBO Workshop on "Membrane fusion in health and disease"
The EMBO Workshop “Membrane Fusion in health and Disease” will cover all aspects of the membrane fusion in eukaryotic organisms. From fusion of organelles within cells, of vesicles with the plasma membrane to release neurotransmitters or other signals, fusion of enveloped viruses to infect a cell, all the way to fusion between cells during fertilisation or during organogenesis. Despite the wide range of processes involving membrane fusion, the molecular mechanisms by which dedicated proteins induce fusion are very similar. Their dysfunction results in anomalies that lead to serious disease or infertility.

Online registration mandatory for Pastorians : 150 €
Institut Pasteur, CIS - From 20 juin 2016 to 24 juin 2016

Contact: Félix Rey (membranefusion2016@pasteur.fr)

XXII International Round Table on Nucleosides, Nucleotides and Nucleic Acids
The congress is jointly organized by french researchers from Institut Pasteur, Université d’Orléans and Université Paris-Descartes, together with the International Society of Nucleosides, Nucleotides and Nucleic Acids (IS3NA, http://conferences_rw.is3na.org).

The dedicated Local Organizers and the top-class Scientific Committee have set-up an exciting scientific program keeping in mind that analogues of nucleosides, nucleotides and oligonucleotides are finding increased applications in biotechnology, biology, and medicine. The XXII IRT will bring together chemists, molecular biologists, biochemists, biologists, medicinal chemists and others, interested in understanding all aspects of this field. The 2016 XXII IRT aims to put at the forefront the latest developments in innovation-driven nucleos(t)ide and oligonucleotide chemistry both in academia and industry, for dealing with the new challenges of our century. The program will feature keynote lectures on following area:

Approved-drugs: from bench to bedside
Anti-cancer, anti-infective and other biologically active nucleos(t)ides
Innovation-driven nucleos(t)ide chemistry
Nucleotide signaling molecules
Synthesis and structure of nucleic acids
Oligonucleotides for therapeutic applications and biotechnology
Biochemistry of nucleosides and nucleic acids

Our young(er) colleagues (Faculty, Post-doctoral fellows, PhD students) are especially welcome to showcase their research (poster and oral presentations) and ideas, and to take advantage of this unique networking opportunity. We also have planned a very rich social program in addition to the scientific program and we suggest that you spend a few extra days in order to really experience the true life and hospitality of Paris.

Online registration mandatory for Pastorians : 150 €
Institut Pasteur - CIS - From 18 juillet 2016 to 22 juillet 2016

Contact: Sylvie Pochet (contact.irt2016@pasteur.fr)

EMBO Conference Tuberculosis 2016: "Interdisciplinary research on tuberculosis and pathogenic mycobacteria"
The EMBO conference “Tuberculosis 2016: Interdisciplinary research on tuberculosis and pathogenic mycobacteria” to be held this year from 19-23 September in the CIS of the Institut Pasteur, will focus on new biological insights and scientific advances on tuberculosis-causing and related pathogenic mycobacteria, and how this knowledge might be used to cope with the enormous problems that pathogenic mycobacteria cause for millions of people today.

Online registration mandatory for Pastorians : 150 €
Institut Pasteur, CIS - From 19 septembre 2016 to 23 septembre 2016

Contact: Roland Brosch (tuberculosis2016@pasteur.fr)

Microbe and Host Lipids
Microbes are found in almost every habitat present in nature and are vital to humans. For instance, the human microbiota has an influence on host physiology. In contrast, some pathogenic microbes can cause infectious diseases, which altogether claim 17 million deaths per year worldwide. Better understanding man and microbes interaction is thus a major public health issue. Indeed, a deeper knowledge of microbiota functions as well as the pathogenic mechanisms developed by microbes will pave the way for the development of new preventive or therapeutic strategies.

Lipids, via their different functions, play a key role in host-microbe interactions. They are essential components of the cell membranes. Some of them are able to modulate host cell functions, and might be used as virulence factors by pathogenic microbes. Manipulation of host lipid metabolism is among the invading strategies evolved by infectious agents, but regulation of host lipid metabolism in physiological conditions also relies on the microbiota. Finally, lipid mediators of inflammation play an essential role in the immune response to infection.

The 12th GERLI lipidomics meeting is part of a series of annual international conferences covering all aspects of lipid research, from advances in basic science to knowledge-based technology, and human health. It will focus on the role of microbe and host lipids in the different contexts of host-microbe interaction. These themes will be developed by some of the most renowned international experts in the field, based on studies dedicated to different types of microbes: bacteria (Pseudomonas, Staphylococcus, Mycobacterium, Shigella, Listeria), fungi (Aspergillus, Candida), viruses (Ebola, hepatitis C) and parasites (Plasmodium).
Toulouse, France - From 23 octobre 2016 to 26 octobre 2016

Contact: Lhousseine Touqui (lhousseine.touqui@pasteur.fr)

Engineering the embryo beyond Systems Biology
Our aim is to bring together scientists from different disciplines but with a shared interest in design principle of living systems, to discuss the possibility of engineering signal and transcription factor circuits to steer cells into particular lineages, tissues and organs in culture with the efficiency and precision of an organism.

Registration is free but mandatory.
Institut Pasteur - Amphithéâtre François Jacob - From 14 novembre 2016 to 15 novembre 2016

Contact: Vania Rosas Magallanes (contact@embryoengineering2016.org)

2016 International Scientific Symposium - Institut Pasteur International Network
From basic science to biomarkers & tools in global health

The 2016 edition of the International Scientific Symposium will be held from November 29 to December 2 on the Paris campus. This annual event, entitled "From basic science to biomarkers and tools in global health", will focus on every aspects of research that can potentially lead to new biomarkers. The event represents a unique opportunity for scientists from all over the world, including scientists working in the International Network, and from both communicable and non-communicable diseases fields, to present their research in the area of global health.

Building on the success of the last two editions, this symposium will again establish a high-level forum for multidisciplinary dialogue and exchanges between all stakeholders involved in Global Health/One Health and thus be an opportunity to create fruitful synergies and promote international collaborations that will source of hope for the world health.

Registration is free for members of the Institut Pasteur International Network.

Abstracts can also be submitted online from May 15 to July 18.
Institut Pasteur, CIS - From 29 novembre 2016 to 02 décembre 2016

Contact: Olivier Rescanière (contact@pasteur-network-meeting2016.org)

Hijacking host signalling and epigenetic mimicry during infections Conference, Juin 2017
Infectious agents can manipulate the genetic program of host cells to gain selective advantage. One major objective is to block the innate immune response of the host organism. However, this is not exclusive. Infectious agents also divert or modify the metabolism of the host cell, manipulating its membranes, intracellular trafficking, and its state of differentiation etc. In some cases, infection can also establish a latent state that leads to long-term persistence. Over the last few years it has become apparent that infections hijack and modify cellular signalling pathways to escape PAMPs recognition, to activate or repress transcription programs, to modify cell cycle progression and the DNA damage response etc.

Furthermore, recent discoveries show that infectious agents can also directly modify the epigenetic landscape of the host cell by activating or inhibiting histone modifications, by histone exchange or histone mimicry, or by modulating chromatin binding proteins etc.

By bringing together scientists with expertise in bacteria, viruses and parasites, (communities that seldom interact), we aim to clarify common and distinct pathways employed during infections by different classes of infectious microbial agents. We hope that the cross-talk between different research communities will generate new ideas and contribute to the development of new therapeutic approaches.

The conference will start on June 13rd at 2 pm followed by a reception. It will terminate on Friday June 17th at 6 pm.

Online registration mandatory for Pastorians : 150 €
Institut Pasteur - CIS - From 13 juin 2017 to 16 juin 2017

Contact: Moshe Yaniv (contact@epigenetics-and-infections2017.org)