En application du plan Vigipirate l'accès à l'Institut Pasteur est subordonné à la présentation d'une pièce d'identité

Workshop on Next Generation Sequencing of Viruses
This workshop, organised by isirv-AVG, GISAID and PREMEDICS, will examine the analysis and interpretation of Next Generation Sequencing (NGS) data of influenza and other viruses, with a particular emphasis on the significance of minor variants within a virus population. It will include discussions relating to sequencing technologies, data processing (quality control, mapping), assembly and analysis of data, database format, interpretation and the significance and use of NGS data for public and animal health.

The fee for this workshop is Euros100 (€100), payable to ISIRV.
This includes refreshments and lunches for both days.
Auditorium François Jacob, Institut Pasteur - From 20 mai 2015 to 21 mai 2015

Contact: Lida DeSouza (lida.desouza@desouza-associates.com)

Mathematical modeling and the potential cure of HIV
Mathematical modeling has been a key part of HIV research since the mid-1990s. I will review some of the important insights gained through modeling so as to set the stage for understanding the possibility of controlling or curing HIV. I will present a new model that provide insights into the phenomenon of post-treatment control in which some patients treated with antiviral therapy have been taken off of therapy and then spontaneously control HIV infection such that the amount of virus in the circulation is maintained undetectable by clinical assays for years. I will also discuss one of the hurdles to true HIV eradication, latently infected cells, and present clinical trial data and a new model addressing pharmacological means of flushing out the latent reservoir.
Institut Pasteur - From 20 mai 2015 to 20 mai 2015

Contact: Romulus BREBAN (romulus.breban@pasteur.fr)

ECCO XXXIV - European Culture Collections as tools in research and biotechnology
The Biological Resource Centre of Institut Pasteur (CRBIP) is pleased to invite you to attend the ECCO meeting 2015 which will be held at the Institut Pasteur in Paris, France from May 27th to 29th . You are all invited to participate in this event, which will bring together the European community of professionals on Microbial Culture Collections, to address the future challenges of Biological Resource Centres, regarding the adaptation to the needs and requirements of academics and bio-industry. The theme of the ECCO XXXIV is: “European Culture Collections as tools in research and biotechnology”. The meeting will be focus on taxonomy/ evolution, biodiversity, omics, regulations and news about MIRRI (Microbial Resource Research Infrastructure: www.mirri.org ) and other ESFRI infrastructures. ECCO meeting is a marvellous opportunity to discover Paris that has much to offer for sightseeing, such as the Louvre museum, the Champs-Élysées avenue, the Eiffel tower, Notre Dame de Paris…Join us in Paris for what promises to be a truly outstanding conference in the field of Culture Collections!
Institut Pasteur Auditorium Jacob - From 27 mai 2015 to 29 mai 2015

Contact: Laure sadier (laure.sadier@pasteur.fr)

Tracking the AIDS Epidemic: Estimating HIV Incidence
HIV incidence is the rate new HIV infections occur in populations. Accurate estimates of incidence are important for tracking the growth of the AIDS epidemic, targeting prevention efforts, and designing prevention trials. Unfortunately, at this point in time, we do not have a single widely accepted method for estimating population HIV incidence levels that is accurate, practical, cost effective and easily implementable. In this talk we discuss limitations with existing methods. We develop methods for estimating HIV incidence rates using multiple biomarkers in biological samples collected from a cross-sectional survey. An advantage of the method is it does not require longitudinal follow-up of individuals. We identify optimal algorithms using multiple biomarkers to estimate incidence that address issues of accuracy, cost and practical issues with implementation. The multiple biomarker approach to cross-sectional HIV incidence estimation is a potentially powerful and practical tool for HIV surveillance.
Institut Pasteur - From 02 juin 2015 to 02 juin 2015

Contact: Romulus BREBAN (romulus.breban@pasteur.fr)

Pathology of Mouse Models for Human Diseases
This workshop provides 3.5 days of up to date training in experimental and comparative pathology. The program will explore mouse models of cancer, diseases of the skin, muscle, bone, special senses, and immune system. It also includes modern imaging technologies and humanized mice models. Macroscopic and histopathological cases will be presented and discussed.

The workshop will start with an afternoon session devoted to recent mouse genetic engineering technologies, phenotyping and strain management.

Attendees will have an opportunity to interact with a group of prominent mouse pathologists from leading research institutions.
Institut Pasteur - Auditorium Centre François Jacob du 16 au 18 juin - Amphithéâtre Monod le 19 juin - From 16 juin 2015 to 19 juin 2015

Contact: Laurence Fiette (laurence.fiette@pasteur.fr)

Neuroscience in Intensive Care International Symposium (NICIS)
The fifth annual conference of this kind devoted to bridging critical care medicine with scientific advances in neuroscience. The symposium is held June 17-19, 2015 at the Institut Pasteur in Paris. The 2015 meeting is titled “Neuroscience of Repair, Regeneration and Recovery from Critical Illness”, and will present groundbreaking research on the biology of neural and muscular recovery following critical illness. NICIS 2015 is endorsed by the University of Versailles, John Hopkins University, and the Institut Pasteur. It is supported by the Neurocritical Care Society, European Society for Intensive Care Medicine, Société Française d’Anesthésie-Réanimation (SFAR), Society for Neuroscience Anesthesia and Critical Care (SNACC), Société Française de Réanimation de Langue Française (SRLF).
Institut Pasteur, Amphithéâtre Duclaux - From 17 juin 2015 to 19 juin 2015

Contact: Pr Tarek Sharshar, (University of Versailles, Institut Pasteur, Paris) (contact@nicis.fr)

Neurosciences in Intensive Care International Symposium (NICIS)
the Neuroscience in Intensive Care International Symposium (NICIS), the fifth annual conference of this kind devoted to bridging critical care medicine with scientific advances in neuroscience. The symposium is held June 18-19, 2015 at the Institut Pasteur in Paris. The 2015 meeting is titled “Neuroscience of Repair, Regeneration and Recovery from Critical Illness”, and will present groundbreaking research on the biology of neural and muscular recovery following critical illness.
Amphithéâtre Duclaux - Institut Pasteur - From 18 juin 2015 to 19 juin 2015

Contact: Tarek Sharshar (tarek.sharshar@pasteur.fr)

Colloque international : « 50 ans après le Prix Nobel. Lwoff, Monod et Jacob comme fondateurs de la biologie moléculaire »
En 1965, le prix Nobel de physiologie fut attribué à André Lwoff, Jacques Monod et François Jacob « pour leurs découvertes concernant le contrôle génétique de la synthèse des enzymes et des virus ». Au-delà du prestige du Nobel, les travaux de ces trois Pasteuriens, souvent réalisés en collaboration avec d’autres collègues (Elie Wollman, Melvin Cohn, etc.), furent reconnus comme l’une des contributions les plus importantes à la constitution de la biologie moléculaire. La manière dont Monod et Jacob conçurent les principes de la régulation génétique devint rapidement essentielle pour comprendre les interactions génétiques et pour envisager le mécanisme de l’embryogenèse chez les métazoaires.
L’objectif de ce colloque est de reconsidérer la signification du modèle de l’opéron à la lumière de l’histoire de la biologie du XXe siècle. Dans un premier temps, nous interrogerons la « préhistoire » du modèle de l’opéron en reprenant l’histoire des deux programmes de recherche qui finirent par converger dans les travaux de Monod et Jacob : celui traitant du mécanisme de l’adaptation enzymatique et celui explorant le phénomène de la lysogénie. La deuxième session est symétrique de la première : nous souhaitons questionner la postérité du modèle de l’opéron et les oppositions qu’il rencontra depuis les années 1960 jusqu’aux années 1990 dans les domaines de la biologie du développement, de la théorie de l’évolution, et de la biologie des systèmes. La dernière session est consacrée à un aspect original de ce moment scientifique : l’étude des liens complexes qui se sont noués entre science, philosophie, éthique et même politique dans le contexte de la fondation de la biologie moléculaire à l’Institut Pasteur.

Institut Pasteur - Amphithéâtre Duclaux - From 28 septembre 2015 to 29 septembre 2015

Contact: Moshe Yaniv (aude.cambon@pasteur.fr)

EMBO Conference : Genetic Control of Development and Evolution
The theme of the EMBO Conference was inspired by seminal studies of François Jacob on gene regulation and by his reflection on evolution expressed in a book published in French in 1981: « Le jeu des possibles, essai sur la diversité du vivant » in an article entitled: “Evolution and Tinkering ” published in Science, 196,1161-1166,1977.

Understanding how organisms evolve and develop in a variety of ecosystems is a major intellectual challenge for humans in general and for experimental biologists in particular. A number of groundbreaking general principles were established following the seminal observations of Darwin and others, yet their molecular foundations remain largely unexplored. This workshop will gather leading scientists whose work with a variety of organisms including yeast, plants, drosophila, butterflies, fish, mice and humans has unravelled the role of gene regulation networks during development, and the generation of organismal diversity. Several key questions will be addressed: 1) Are small changes in cis regulatory elements or in the specificity of transcription factors sufficient to drive evolution and generate diversity? 2) What are the roles of synergy and complex regulatory elements? 3) How does epigenetic regulation underwrite these processes? Our focus is not on the detailed transcription machinery itself, but rather its deployment in the generation of diversity. The workshop also includes several talks on the effect of our environment on evolution and adaptation.

The EMBO conference will start on September 29th at 6pm with a keynote talk by David Allis followed by a reception. It will terminate on Friday October 2nd at 6pm.
Institut Pasteur - CIS - From 29 septembre 2015 to 02 octobre 2015

Contact: Moshe Yaniv (moshe.yaniv@pasteur.fr)

Fungal Cell Wall 2015
We are delighted to announce the Fungal Cell Wall 2015 meeting to be held on the campus of the Institut Pasteur in Paris from 26-28 October, 2015. This meeting will gather the leaders in fungal cell wall biology, immunology, and antifungal mechanisms to exchange new ideas and forge new collaborations.

Previously, there have been several successful but separate fungal cell wall meetings (including Ascona, 2001, Salamanca, 2003, Heidelberg, 2006, Biarritz 2007,and Giens 2011), each with different focus: model fungi, plant pathogens human pathogens, and even the plant cell wall. This meeting will gather, for the first time, the entire cell wall community. For this Fungal Cell Wall 2015 meeting, we are merging in order to generate a more comprehensive conference that will cover all aspects related to the fungal cell wall, from fundamental to applied research.

A unique and prominent feature of fungi is that they are surrounded by a cell wall. All exchanges between a fungal cell and its environment rely upon a functional and permeable cell wall. The cell wall is continuously in contact with the host and acts as a sieve and a reservoir for effector molecules such as antigens and enzymes that play an active role during infection. The cell wall is therefore essential for fungal growth, as well as for resisting environmental stresses such as phagocytic killing.

Cell wall biosynthetic enzymes represent unique drug targets. In the last 10 years, major discoveries in cell wall biology were achieved in an amazing diversity of disciplines, including biochemistry, cellular and molecular biology, genetics, immunology and host defense interactions, and biophysics. These breakthroughs are contributing to a better understanding of the cell wall and its role in fungal infections in human and plants.

There will be approximately 25 invited speakers at the meeting, and numerous spots have been reserved for oral presentations that will be selected from the submitted abstracts. Ample space will be available for poster display.
Institut Pasteur - CIS - From 26 octobre 2015 to 28 octobre 2015

Contact: Jean-Paul LATGE (fcw2015@pasteur.fr)